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A 12-month program of regular exercise in selected patients with chronic stable angina and significant CAD resulted in a higher event-free survival and exercise capacity at lower costs than PCI.
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Drs. Stuart Connolly and Stefan Hohnloser presented results from the Defibrillator In Acute Myocardial Infarction Trial (DINAMIT). Prior studies had shown that patients with recent myocardial infarction and left ventricular dysfunction are at high risk for death in the period after myocardial infarction.
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Although beta-blockers are known to reduce the sensitivity of exercise and dobutamine sestamibi SPECT imaging for the detection of coronary artery disease, little is known about their effects on vasodilator stress scintigraphy. Thus, Taillefer and colleagues studied 21 patients with catheter proven coronary artery disease during 3 different treatments on different days assigned in a random fashion.
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A United Kingdom survey of sudden arrhythmic death syndrome in 32 victims aged 4-64 with normal hearts at autopsy and a negative toxicologic screening test evaluated first-degree relatives of these victims.
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In this paper, Oral and colleagues compared 2 current ablation techniques in patients with paroxysmal atrial fibrillation.
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This widely publicized small trial has catapulted the mutant form of ApoA-1 Milano into the limelight. Many investigators have been working with this interesting lipoprotein since it was discovered in the 1980s that 38 carriers from a small village in Northern Italy have very low HDL levels but very little vascular disease.
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Oral rofecoxib (Vioxx) may have a role in controlling postoperative pain patients undergoing knee surgery.
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In patients with acute anterior myocardial infarction the significance of inferior ECG ST-segment elevation is unclear. Thus, investigators from the GUSTO-I angiographic and the GUSTO-IIb angioplasty substudies evaluated the 1046 patients with anterior ST elevation and divided them into 3 groups.
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Talreja and colleagues from the Mayo Clinic in Rochester, Minn, reviewed biopsy specimens and clinical features of 143 patients who had pericardiectomy for proven pericardial constriction.
