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Since aldosterone is extracted by the heart following acute myocardial infarction (MI), this group of investigators from Japan hypothesized that blocking its action may attenuate postinfarction remodeling.
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Cardiac resynchronization therapy improves quality of life and New York Heart Association Functional class in patients with moderate-to-severe heart failure, wide QRS durations, and indications for an ICD.
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The combined infusion of AVP and NE was superior to NE alone in catecholamine-resistant vasodilatory shock.
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Since patients with low gradient aortic stenosis are at higher risk for surgical replacement, more information concerning whom to select for surgery is desirable. Monin and colleagues from 6 centers in France studied 136 symptomatic patients with aortic valve area < 1.0 cm2, low cardiac index and a mean aortic pressure gradient < 40 mm Hg.
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Prognostic Value of ABPMs in patients with Treated Hypertension;
Tazarotene Cream in the Treatment of Psoriasis; Antihyperglycemic
Effect of Oolong Tea in Type 2 Diabetes; Metformin and
Thiazolidinedione Use in Medicare Patients with Heart Failure; Alcohol
Consumption Patterns and Biologic Markers of Glycemic Control; Azelaic
Acid Gel as a New Treatment for Papulopustular Rosacea
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Another study has shown an increase in mortality associated with the use of an oral IIb/IIIa receptor antagonist.
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The Task Force on Valvular Regurgitation of the American Society of Echocardiography, in conjunction with the ACC, AHA, and ESC, has published recommendations for evaluating the severity of native valvular regurgitation by echocardiography. Unfortunately, the task force did not come up with a simple foolproof system.
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Although mitral valve repair for mitral regurgitation is gaining in popularity, there are little comparative data with mitral valve replacement. Thus, Thourani and colleagues performed a case-controlled observational study of the Emory University Hospitals surgical database, matching 625 patients undergoing mitral valve repair with 625 undergoing mitral valve replacement from 1984 to 1997.
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Mitchell and colleagues examined the association between therapy with lipid-lowering drugs and recurrent arrhythmias in the Antiarrhythmics Versus Implantable Defibrillators trial.
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Pappone and colleagues present an observational study evaluating the efficacy of their laboratorys technique for pulmonary vein isolation.
