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In one of the more bizarre stories of the year, the FDA has uncovered files of counterfeit Procrit (epoetin alfaJohnson & Johnson) in routine surveillance. To make matters worse, the fake vials have been contaminated with bacteria and many contain no active ingredient.
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Editors Note: The following reports from the annual scientific sessions of the American College of Cardiology held March 30 to April 2, 2003, were obtained by handwritten notes, press releases, and news reports.
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Increase in Blood Glucose Concentration During Antihypertensive
Treatment as a Predictor of Myocardial Infarction; Adverse Drug Events
in Ambulatory Care; Prevention of Hip Fracture by External Hip
Protectors; Rapid MRI vs Radiographs for Patients with Low Back Pain;
Effectiveness of Anticholinergic Drugs Compared with Placebo in the
Treatment of Overactive Bladder; A Randomized Trial of a Low
Carbohydrate Diet for Obesity
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Nasally Administered Flu Vaccine Comes to United States; Paxil: Not Recommended for Children; Prilosec Granted OTC Status; Finasteride and Prostate Cancer; Xolair: First Biologic Agent for Asthma; West Nile Virus Update; Study Shows COX-2 Inhibitors Appear Safe with Aspirin in Asthma Patients; Lamictal Approved for Bipolar Disorder
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This report is a detailed analysis of the approximate 6000 diabetics in the Heart Protection Study, which investigated the efficacy of simvastatin (simva) and antioxidant vitamins.
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Sweeney and colleagues from the Mode Selection Trial report on the effects of ventricular pacing in patients with sinus node dysfunction.
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Sutton and colleagues from New Zealand explored the concept that natriuretic peptide levels (ANP, BNP) may aide in the determination of the severity of mitral regurgitation.
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Current supportive heart failure therapy has reduced morbidity and mortality, but adverse outcomes are still frequent. Clearly, an approach based upon eliminating the cause of myocardial dysfunction would be advantageous. This study is an attempt to pursue this line of therapy for viral myocarditis using the antiviral agent INFB.
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This study, following on the heels of the recent negative trial in postpercutaneous coronary stenting patients, suggests that we have more to learn about the role of folic acid and homocysteine in CAD.