Childhood Cancer
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Bisphosphonates and Long-term Survival in Breast Cancer
The role of bisphosphonates in the treatment and prevention of bone metastases remains incompletely characterized. In the current report, Diel et al detail long-term survival data on patients with known microscopic bone disease more than eight years after adjuvant treatment with clodronate. -
Thalidomide-rituximab for Waldenstrom Macroglobulinemia
Thalidomide-rituximab was administered to 25 symptomatic patients (20 previously untreated) with Waldenstrom macroglobulinemia. The overall response rate was 72%, and the median time-to-progression for responders was 38 months. -
Prevalent vs Incident PSA Screen-detected Prostate Cancer
Among patients who undergo screening and are diagnosed with prostate cancer, there is a dichotomy between those who are diagnosed after their initial screening (prevalent cases) and those who have cancer detected after subsequent screenings (incident cases). -
FLOT: An Effective Regimen for Gastric or Gastro-esophageal Cancer
A new regimen (fluorouracil, leucovorin, oxaliplatin, and docetaxel [FLOT]) was tested in a phase II trial in 54 patients with gastric or gastro-esophageal cancer. Response rates were comparable, or perhaps even a little better than those published for other combinations; the toxicity profile appears favorable. -
Clinical Briefs in Primary Care Supplement
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Pharmacology Watch
The JUPITER trial causes a stir; ACP practice guideline for antidepressant use; testosterone for low libido; continued shortage of Hib vaccine; FDA Actions. -
Survival after Laparoscopy in Women with Endometrial Cancer
Eltabbakh retrospectively reviewed women presenting with clinical stage I endometrial cancer (according to the 1988 FIGO staging) at the University of Vermont. -
Clinical Briefs in Primary Care Supplement
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Clinical Briefs in Primary Care
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Correcting Warfarin-Induced Coagulopathy: Low-Dose Oral Vitamin K is Not Only Sufficient — Its Better!