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The Biventricular vs Right Ventricular Pacing in Heart Failure Patients with Atrioventricular Block (BLOCK HF) trial tested the hypothesis that biventricular pacing (cardiac resynchronization therapy [CRT]) would be superior to right ventricular pacing in patients with mild-to-moderate heart failure, left ventricular systolic dysfunction, and an indication for full-time ventricular pacing.
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The Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) trial was completed more than 10 years ago.
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Patients seen in emergency departments (ED) for acute chest pain who are deemed low risk for acute coronary syndrome (ACS) and relatively safe for discharge are often referred to their primary care physician (PCP) for follow-up.
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Beta-blockers and noncardiac surgery; prenatal medication exposure and risk of autism; reasons for statin discontinuations; and FDA actions.
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Guideline-driven earlier mitral valve repair for patients with mitral regurgitation (MR) due to degenerative disease has increased in the last 25 years.
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Many patients need to take long-term oral anticoagulants (OAC) for indications such as atrial fibrillation (AF) or mechanical prosthetic valves.
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The decision to choose a mechanical or a tissue valve for patients undergoing surgical aortic valve replacement (AVR) is a complex one that involves synthesizing clinical factors such as risk of bleeding, likelihood of reoperation, and patient preference. Increasingly, older patients with more comorbidities are being referred for AVR surgery.
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Atrial septal defects (ASD) can lead to exercise intolerance, pulmonary hypertension, right heart failure, and reduced life expectancy if they are not repaired. Surgical closure for ASD transformed the care of these patients and resulted in similar life expectancy to subjects without ASD. In recent years, transcatheter ASD closure has largely replaced surgery, but long-term data comparing the two techniques are limited.
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Elevated troponin levels after non-cardiac surgery have been shown to predict postoperative myocardial infarction (MI) and death. Thus, these investigators from the Netherlands instituted a postoperative troponin monitoring program at one hospital to test the hypothesis that troponin elevations in the first 3 days after surgery would predict 30-day mortality after non-cardiac surgery.
