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It is well known that the risk of perioperative major adverse cardiac events (MACE) is high in patients with coronary stents, especially early after stent implantation.
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Newer bileaflet mechanical heart valves require lower doses of oral anticoagulants to avoid valve thrombosis and embolism genesis. However, little is known about the safety of low-dose regimens in pregnant women who have a hypercoagulable state, yet warfarin embryopathy is known to be dose related.
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Drug shortages; metformin and cancer prevention; migraine prevention guidelines; and FDA actions.
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These investigators from Australia present a case of isolated left ventricular (LV) apical hypoplasia with fatty infiltration confirmed by CT and MRI. The left anterior descending artery was small and truncated early on angiography. Echocardiography showed a large banana-shaped right ventricle (RV) that wrapped around the apex of the hypocontractile truncated LV. Also there was apical papillary muscle insertion.
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In this paper, the authors performed a pharmacoepidemiologic study on the relationship between azithromycin, a frequently used broad-spectrum macrolide antibiotic, and cardiovascular death. The authors analyzed data from the Tennessee Medicaid program. This database provides information on medical care encounters and dates and causes of death and is linked to death certificates and hospital discharge data.
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Azithromycin and cardiac risk; warfarin and heart failure; aspirin and VTE; effectiveness of long-acting contraceptives; and FDA actions.
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This interesting study examined a new technique for exploring the mechanism(s) for atrial fibrillation (AF). Patients scheduled for catheter ablation of paroxysmal or persistent AF were recruited for the study. Antiarrhythmic drugs were stopped before the study was performed.
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More than 200,000 Riata family implantable cardioverter-defibrillator (ICD) leads from St. Jude Medical were implanted worldwide. Recently, the FDA issued a Class I recall on this lead because of the appearance of defects in the lead insulation that may lead to externalization of the conductor wires.
