Cardiology
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Cheyne-Stokes Respiration in Heart Failure
A comprehensive cardiorespiratory study of stable systolic heart failure patients showed Cheyne-Stokes breathing in the awake, upright position is related to hypercapnia and is independently associated with a higher risk of cardiac death.
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Can Antibiotics Sterilize an Infected Heart Valve Before Surgery?
In a study of the relationship between the duration of antibiotic therapy and a positive surgically excised heart valve culture in patients with infective endocarditis, researchers observed positive valve culture incidence decreases exponentially on antibiotic therapy for 14 days then plateaus with no effect after 21 days of therapy.
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The Prognosis of Severe Mitral Annular Calcification
This retrospective review of the natural history of severe calcific mitral valve stenosis demonstrates such patients die often partly because of a high comorbidity burden and partly as a result of the valve stenosis.
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Renal Denervation Makes a Comeback
This retrospective review of the natural history of severe calcific mitral valve stenosis demonstrated such patients have a high mortality partly because of a high comorbidity burden and partly because of valve stenosis. Although often symptomatic, symptoms did not predict mortality.
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Insulin Lispro-aabc Injection (Lyumjev)
Lyumjev is indicated to improve glycemic control in adults with diabetes mellitus.
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Clostridioides difficile: Risk Factors for Disease
Approximately one-tenth of asymptomatic patients with Clostridioides difficile colonization went on to develop disease. A wide range of antibiotic exposures represent a significant risk.
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Benefits of Exercise in Established Atrial Fibrillation
A large, long-term, prospective, Norwegian population study of patients with established atrial fibrillation revealed physical activity at or above recommended levels reduces all-cause and cardiovascular mortality vs. atrial fibrillation patients who are inactive.
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Eat Flavonoids for a Healthy Brain
An investigation of the Framingham Offspring Study revealed a higher intake of dietary flavonoids found in plants is associated with modest slowing of age-related dementia.
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Neurologic Manifestations of Hospitalized Patients with COVID-19 in Wuhan, China
Neurological symptoms and impairments have been found in one-third of hospitalized patients with COVID-19 from countries that have reported these observations so far. This is a rapidly evolving consequence of SARS-CoV-2 infection.
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Androgen Deprivation Therapy and SARS-CoV-2
Cancer patients are at a higher risk of contracting SARS-CoV-2 vs. non-cancer patients. However, prostate cancer patients who received androgen deprivation therapy seem to be partially protected from such infections.