Cardiology
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Estrogen Replacement: Is Long Duration of Therapy Good for the Brain?
Longer lifetime exposure to endogenous estrogen and menopausal estrogen replacement were associated with better cognitive status in older adult women.
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Heart Failure Confers Increased Risk of Venous Thromboembolic Events
In the Atherosclerosis Risk in Communities (ARIC) cohort, incident heart failure hospitalization with either preserved or reduced ejection fraction was associated with long-term increased risk of venous thromboembolic events.
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For Knee Arthritis: Physical Therapy or the Needle?
In a small, randomized, controlled trial of patients with knee osteoarthritis, those who received physical therapy reported less pain and functional disability at one year than those who received one or more glucocorticoid intra-articular injections. -
Empiric Anti-MRSA Therapy in Pneumonia May Not Always Be a Good Idea
In a retrospective cohort study, empiric anti-methicillin-resistant Staphylococcus aureus treatment was not associated with a reduction in mortality in any subgroup of patients studied and appeared to cause harm in many.
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Investigators Uncover More Troubling Data About the Adverse Health Effects of Sugar-Sweetened Beverages
Recent study revealed women who consume just one such beverage per day were at a much higher risk for stroke and cardiovascular disease.
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Early Data on Remdesivir for Severe COVID-19: A Promising Start?
In this group of patients hospitalized with severe COVID-19, the majority of whom required invasive ventilation, 68% showed clinical improvement after treatment with remdesivir on a compassionate-use basis.
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Anticoagulation Therapy in Patients with Severe COVID-19
In a retrospective study involving 449 patients with severe COVID-19 requiring intensive care unit admission, those patients with a positive sepsis coagulation score or D-dimer greater than 3.0 mcg/mL who received prophylactic doses of low molecular weight heparin exhibited lower 28-day mortality.
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Managing COVID-19 Respiratory Failure: Is There a Perfect Management Strategy?
COVID-19 is a systemic disease that primarily injures the vascular endothelium, causing a unique lung injury in which different management strategies may need to be considered to address the specific physiology of each patient.
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Group Leads Charge Against Venous Thromboembolism
The American Heart Association issues guidance to help prevent a common and costly hospital-acquired condition.
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MUCH Ado About WUCH
In a long-term, fixed-drug therapy of hypertension study, masked uncontrolled and white coat uncontrolled hypertension exhibited poor reproducibility over four years. This calls into question studies showing higher rates of adverse outcomes with one baseline blood pressure assessment used to categorize patients.