Cardiology
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Large Systematic Review of Vitamin and Antioxidant Supplements Finds No Impact on Risk of Cardiovascular Disease
A systematic review and meta-analysis of 50 randomized controlled trials did not find that vitamin and antioxidant supplements reduce the risk of cardiovascular disease. Numerous subgroup analyses similarly found no benefit from daily supplementation, but also no adverse effects. -
Plant-based Diets for Cardiovascular Disease: A Brief Review
Although very interesting research exists for the effects of isolated phytonutrients on many different disease processes, just as compelling is the resurgence in research on whole plants or whole food approaches to promoting health or treating disease (e.g., investigating a multi-component, plant-based dietary pattern and disease vs investigating the consumption of beta-carotene and disease). -
Integrative Medicine Alert - Full April 2013 Issue in PDF
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Early use of Daptomycin Compared to Vancomycin for MRSA Bacteremia
In a matched, retrospective cohort study, early use of daptomycin compared to vancomycin in MRSA bacteremia with vancomycin MICs > 1 µg/mL resulted in improved clinical outcomes, including less clinical failure at 30 days, lower mortality and less persistent bacteremia. -
Macrolide Antibiotics May Increase the Risk of Statin Toxicity
The toxicity of statins was increased in older adults who were coprescribed the CYP3A4 inhibitors clarithromycin or erythromycin. -
Overnight Vital Signs — Are They Always Beneficial?
Low MEWS score may be beneficial in identifying a subset of hospitalized patients unlikely to benefit from nocturnal vital sign monitoring. -
Hospital Medicine Alert - Full August 2013 Issue in PDF
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Chest Pain and Dyspnea? Taking Steroids? Think PE.
Corticosteroid use is associated with an increased risk of symptomatic pulmonary embolism. The greatest risk is in the first 30 days of use and increases with increasing steroid dose. -
Internal Medicine Alert - Full December 29, 2013 Issue in PDF
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