Cardiology
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Childhood Sleep Difficulties and Adolescent Mental Health
This prospective United Kingdom study involving 13,488 children shows an association between specific early childhood sleep problems and symptoms of psychosis in adolescence. Another specified early childhood sleep problem is associated with symptoms of borderline personality disorder in adolescence.
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Air Pollution and Cognitive Decline
SYNOPSIS: In this large prospective cohort study of subjects in Manhattan, researchers demonstrated an association between exposure to air pollution and decline in cognitive function over time in one cohort, but not the other.
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Norepinephrine Infusion Through Peripheral Intravenous Lines: Is it Safe?
In a large perioperative patient population, norepinephrine infusion through peripheral intravenous lines did not result in any significant adverse events. However, the specific patient population, limited duration of infusion, and hospital setting may limit the generalizability of these findings.
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Do We Really Know the Optimal Oxygen Target in Patients with ARDS?
In the LOCO2 study, a conservative oxygen strategy with SpO2 goals of 88% to 92% was not shown to improve mortality over a liberal oxygen strategy as hypothesized, but rather was found to have a worrisome signal of increased mortality and increased mesenteric ischemia.
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Management of Pulmonary-Renal Syndrome
The role of the intensivist in the management of pulmonary-renal syndrome includes appropriate respiratory support and recognition and management of concurrent infection, hypovolemia, acute anemia, and coagulopathy.
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Veterans with PTSD, TBI at Much Higher Risk for Heart Attack
Such patients also more likely to experience first attack at a younger age than the general population.
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Remdesivir Injection (Veklury)
Remdesivir’s benefit appears to be modest, but may be better for those receiving low-flow oxygen.
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Can Chopsticks Carry SARS-CoV-2?
This small study suggests salivary contamination of utensils with SARS-CoV-2 virus can occur. Sharing food and utensils, or using communal food bowls, probably is not a good idea if one is trying to avoid COVID-19.
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Possible Aerosol Spread of SARS-CoV-2 in an Apartment Building
Although not definitive, evidence is consistent with aerosol spread of SARS-CoV-2 in an apartment building as a result of transport through the drainage system to apartments directly above.
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A Novel Rifabutin-Containing Combination Regimen Eradicates H. pylori Infection
Researchers found a significantly higher eradication rate for H. pylori with a 14-day regimen of rifabutin, amoxicillin, and omeprazole compared to 14 days of amoxicillin and omeprazole.