Cardiology
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COVID-19 ARDS Is Associated with Higher Compliance and Lung Gas Volume Compared to Non-COVID-19 ARDS
This retrospective analysis compared historical cohorts with COVID-19-related acute respiratory distress syndrome (ARDS) with respect to compliance and arterial partial pressure of oxygen/fraction of inspired oxygen (P/F) ratios. For comparable P/F ratios, patients with ARDS caused by COVID-19 had higher lung compliance and more lung gas volume.
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Noninvasive Ventilation in Adult Acute Care: Beyond Clinical Indications
Noninvasive ventilation (NIV) is a commonly used modality in adult acute care. This article examines aspects of NIV that might affect the modality’s success or failure.
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Evinacumab-dgnb Injection (Evkeeza)
Evinacumab-dgnb should be prescribed as an adjunct to other low-density lipoprotein cholesterol-lowering therapy to treat patients age 12 years and older with homozygous familial hypercholesterolemia.
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Prednisone vs. Placebo in Short-Term Prevention of Episodic Cluster Headaches
Prednisone, given at 100 mg for five days and then tapering by 20 mg every three days, is a safe and effective short-term prevention for episodic cluster headaches while waiting for longer-acting preventive agents to be initiated.
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Early Convalescent Plasma to Treat COVID-19 in Elderly Patients with Mild Symptoms
Administering convalescent plasma obtained from survivors of COVID-19 within 72 hours of onset of mild symptoms in elderly patients with the virus was associated with a significant reduction in the risk of development of severe respiratory disease.
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COVID-19 Patients Can Be Managed Safely with Noninvasive Respiratory Techniques
In adult patients hospitalized with COVID-19 for one month, using a noninvasive respiratory protocol that encouraged high-flow nasal cannula, noninvasive mechanical ventilation, and self-proning did not result in any significant increase in mortality.
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Healthcare Workers with COVID-19 Antibodies: Strong Protection Against Reinfection
A study of healthcare workers demonstrated the presence of antibody to SARS-CoV-2 spike protein or to nucleocapsid provides strong protection against infection for up to six months.
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THC-Related Neuropsychiatric Symptoms in Older Adults
Using cannabis-based medicine often exposes patients to delta-9-tetrahydrocannabinol (THC), which is associated with psychotic symptoms. THC also can cause lightheadedness, dizziness, and thinking or perception disorder in older adults.
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Low BNP Levels in Up to 16% of Heart Failure Patients
In patients with clinical heart failure and low B-type natriuretic peptide levels, the authors found these patients usually are young and obese, with higher ejection fraction and better renal function.
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PFO Closure for Resistant Migraines: Finding an Elusive Link
A meta-analysis of two randomized trials of patent foramen ovale closure in resistant migraine showed a significant benefit in three of four clinical endpoints.