Cardiology
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Using His Bundle Pacing for Cardiac Resynchronization: Does It Hold Up to the Standard?
In a randomized trial of patients with heart failure and left bundle branch block, cardiac resynchronization therapy via permanent His bundle pacing produced similar short-term outcomes to traditional biventricular pacing, albeit with higher pacing thresholds.
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STEMI in Post-Transcatheter Aortic Valve Replacement Patients
This large series of post-transcatheter aortic valve replacement patients with ST-elevation myocardial infarction demonstrates elevated rates of percutaneous coronary intervention failure and high short- and intermediate-term mortality rates.
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Another Way Antibiotic Therapy Can Kill You
An analysis revealed fluoroquinolone antibiotic use was associated with later aortic diseases and mortality in patients without known aortic disease.
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Aortic Aneurysm Claims Generate Highest Average Indemnity for ED
ED malpractice claims involving aortic aneurysm generated higher average indemnity ($369,872) than any other medical condition, according to a recent analysis. Failure to timely diagnose is the most common allegation in malpractice actions, followed closely by poor communication between providers.
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What Is the Rhythm? What Is the Culprit Artery?
The ECG in the figure was obtained from a middle-aged man with chest pain. What can one say about the cardiac rhythm? How can one determine the “culprit” artery?
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Viloxazine Extended-Release Capsules (Qelbree)
Viloxazine should be prescribed to treat ADHD in patients age 6 to 17 years.
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Exercise Intervention for Improving Metabolic-Associated Fatty Liver Disease
Researchers assessed the histological appearance of liver biopsies from patients with metabolic-associated fatty liver disease (MAFLD) who completed 12 weeks of structured and supported aerobic exercise. Compared to biopsies from a nonexercising control group, the intervention arm demonstrated some reversal of histopathologic changes caused by MAFLD.
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Intracranial Plaque Rupture and Stroke
An MRI study of cerebral circulation in patients with embolic stroke of undetermined etiology showed evidence of atherosclerotic plaque in most patients.
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Ketogenic Diet Improves Cognition, Daily Function in Alzheimer’s Disease Patients
In a randomized, crossover trial, patients with Alzheimer’s disease on a ketogenic diet for 12 weeks demonstrated improved cognition, daily function, and quality of life.
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Transdiagnostic Cognitive Behavioral Therapy in Young Patients
This Danish randomized clinical trial compares a new form of cognitive behavioral therapy delivered in a community setting to “treatment as usual” for children and teens with emotional problems and shows advantages in multiple arenas, including parent-reported changes in child distress and impairment.