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Amgen has received approval to market palifermin. The drug is approved to decrease the incidence and duration of severe oral mucositis in patients with hematologic malignancies undergoing chemotherapy, with or without radiation, followed by a bone marrow transplant.
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With their variable and unpredictable results, bites and stings can be vexing for the ED physician to assess and treat. The purpose of this paper is to provide an overview for treatment of the most important bites and stings encountered in the United States. Due to the popularity of the exotic pet trade, some non-native species now commonly held in captivity in private homes in the United States also will be discussed, especially when specific anti-venom is available.
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In patients with heart failure and cardiac dyssynchrony, cardiac resynchronization improves symptoms and the quality of life and reduces complications and the risk of death.
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In patients 75 years of age or younger who have myocardial infarction with ST-segment elevation and who receive aspirin and a standard fibrinolytic regimen, the addition of clopidogrel improves the patency rate of the infarct-related artery and reduces ischemic complications.
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Intensive lipid-lowering therapy with 80 mg of atorvastatin per day in patients with stable CHD provides significant clinical benefit beyond that afforded by treatment with 10 mg of atorvastatin per day.
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Seven trials comparing drug eluting stents to each other
or bare metal stents were presented. In general, they showed that
drug eluting stents were superior to bare metal stents, but among the
drug eluting stents, the data favored sirolimus eluting stents.
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The possibility of a bird flu pandemic has health officials worldwide in a high state of alert.
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Patients with HCM exhibit a high frequency of ventricular and supraventricular arrhythmias during ambulatory ECG monitoring, but sudden death is uncommon and not predicted by arrhythmias.