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Aspirin, Higher Doses No More Effective, Risky; Subclinical Hypothyroidism Treatment Benefits; FDA approvals
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Using laboratory results from a recent 30-month period for case finding, Lamontagne and colleagues reviewed the medical records of all patients with fulminant Clostridium difficile-associated disease (CDAD) who received care in the ICUs of 2 tertiary-care hospitals in Quebec.
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The objective of this study was to evaluate the role of patient-ventilator dys-synchrony in the etiology of sleep disruption, and to determine whether optimizing patient-ventilator interactions by using proportional assist ventilation (PAV) improves sleep.
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The literature on the technical and clinical aspects of mechanical ventilation for patients with acute respiratory failure continues to expand, with nearly 50,000 citations appearing in PubMed for the topic "mechanical ventilation," and more than a thousand articles in English reporting the results of clinical trials under this heading published during the last 5 years.
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GlaxoSmithKline's rosiglitazone (Avandia) will receive a black box warning by the FDA because of concerns over heart failure associated with use of the drug.
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The biochemical analysis of pericardial fluid is often done routinely, but there is little data on its value. Thus, these investigators from Israel retrospectively analyzed all pericardiocentesis patients over a 9-year period by chart review and phone calls.
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Although Mitral Annular Calcium (MAC) is a risk for stroke, the mechanism is unclear. MAC is associated with complex proximal aorta (before the left subclavian) aorta atheromatous plaques and is seen in patients with risk factors for atherosclerosis.
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Up to 20% of patients undergoing coronary angiography have normal arteries or mild luminal irregularities.