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The FDA has approved the first of a new class of anti-HIV drugs. Maraviroc is a selective CCR5 co-receptor antagonist.
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Frequent atrial premature beats predict paroxysmal atrial fibrillation in stroke patients: An opportunity for a new diagnostic strategy.
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Elevated non-fasting triglyceride levels are associated with incident cardiovascular events independent of traditional cardiac risk factors, levels of other lipids, and markers of insulin resistance; by contrast, fasting triglyceride levels demonstrated little independent relationship to these events.
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Compared with morbidly obese individuals who did not have surgery, those who underwent gastric bypass surgery had reduced total mortality after about 7 years, especially for deaths from diabetes, heart disease, and cancer. However, the rate of death from accidents and suicides was higher in the surgery group than in the control group.
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Meta-analysis (META) is intended to provide greater strength of evidence by combining like populations of similar clinical trials in similar circumstances. Unfortunately, no two populations or sets of circumstances are identical, resulting in conclusions being drawn from large data sets which may not be reliable.
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These investigators describe the results of once a week rosuvastatin in 10 patients intolerant to once-a-day statins due to myalgias, high liver function tests and gastrointestinal side effects.
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Heart failure with normal left ventricular (LV) systolic function is thought to be due to diastolic dysfunction in most cases, but confirming LV diastolic dysfunction by echo Doppler techniques is often challenging.
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Surgical aortic valve replacement (avr) remains the gold standard treatment for patients with severe aortic stenosis (AS). However, a number of patients are at increased risk of mortality during AVR due to advanced age or co-morbidities.