Cardiology
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Clostridioides difficile Infection: Guideline Update
Fidaxomicin is preferred over vancomycin for initial and recurrent cases. Bezlotoxumab is recommended in many cases of recurrent infection and initial infection in patients at high risk of recurrence.
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Can Antibiotics Lead to Colon Cancer?
Swedish researchers saw an association between frequent antibiotic use and proximal colorectal cancer.
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Adverse Effects of Electronic Cigarettes on the Disease-Naïve Oral Microbiome
A robust metagenomic comparison study of the effects of electronic cigarettes on oral microbiomes suggested the unique aerosol component of electronic cigarettes poses increased risk to development of oral cavity disease.
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Aftermath of COVID-19 in Adults
This review of investigations centered on long-term effects following acute COVID-19 illness in adults illustrates an evolving understanding of the aftermath of this viral infection.
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Is There a Difference Between COVID-19 and Non-COVID-19 ARDS?
Comparison of a small COVID-19 acute respiratory distress syndrome (ARDS) cohort with a historical pre-COVID-19 ARDS cohort found some differences in physiologic parameters and biomarkers, but not enough evidence to warrant deviation from known management guidelines.
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Beyond Benzodiazepines: Adjuncts for the Management of Alcohol Withdrawal in the ICU
Although benzodiazepines are the mainstay of prevention and treatment of alcohol withdrawal syndrome, adjunct medications are used increasingly, with the goal of reducing cumulative benzodiazepine exposure and decreasing both hospital and intensive care unit admission and length of stay.
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COVID-19 Vaccine mRNA Injection (Comirnaty)
Comirnaty is the first COVID-19 vaccine to receive full FDA approval.
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Functional Cognitive Disorder: An Important Condition to Recognize
Functional cognitive disorder (FCD) can describe cognitive difficulties that are present where there is no biologic cause, but a lack of consensus in diagnostic criteria limits its use in clinical practice and research. The authors proposed an operational definition for FCD as the cognitive phenotype of functional neurological disorder.
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Vitamin and Mineral Supplements for Cardiovascular Disease
A meta-analysis of systematic reviews and randomized, controlled trials to analyze the role of commonly used dietary supplements for prevention and treatment of cardiovascular disease suggests no significant effect on cardiovascular outcomes or all-cause mortality, although some B vitamins appear to reduce stroke incidence, and B3 appears to increase all-cause mortality.
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Fermented Foods Help the Immune System, Alleviate Inflammation
A diet rich in fermented foods from dairy and other sources reduced 19 inflammatory markers compared with a high-fiber diet.