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FDA warning on topical anesthetics; antipsychotics increase sudden cardiac death; the step up vs step down debate; treating pain, fatigue, mood, and sleep in fibromyalgia; FDA Actions.
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In this paper, stevenson et al, from 18 centers with expertise in ventricular tachycardia (VT) ablation, report the results of VT ablation using the Thermo°Cool-irrigated, tipped-radiofrequency ablation catheter. Patients were eligible for the study if they had multiple episodes of sustained monomorphic VT that had required either cardioversion or antiarrhythmic drug administration in the previous six months.
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Small studies with older equipment at single centers have shown that coronary CT angiography (CTA) is promising for evaluating coronary anatomy. New 64-slice CT scanners have improved spatial and temporal resolution. Thus, these investigators from the Netherlands conducted a prospective, multi-centered, multi-vendor study to assess the accuracy of 64-slice CTA for in dentifying significant coronary artery disease (CAD) in symptomatic patients undergoing conventional coronary angiography (CCA).
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In this issue: FDA warning on topical anesthetics; antipsychotics increase sudden cardiac death; the step up vs step down debate; treating pain, fatigue, mood, and sleep in fibromyalgia; FDA Actions.
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This study from the University of Toronto sought to quantify the number of individual pieces of clinical information entered into the medical record on each patient in the ICU each day.
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Pulmonary hypertension (ph) is common among patients in the intensive care unit (ICU). In fact, many ICU clinicians simply view PH the same way they view leukocytosis as an expected finding caused by the "bigger problems" of sepsis, respiratory failure, congestive heart failure, volume overload, and myocardial infarction.
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Despite concerns that recombinant human Activated Protein C (rhAPC) is associated with an increased risk of bleeding, the FDA failed to list several of the bleeding-related exclusion criteria used in the PROWESS trial as contraindications to use of this agent.