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The clinical utility of microvolt T-wave alternans (MWTA) testing to detect subtle beat-to-beat oscillations in the electrocardiogram's T-wave amplitude as a non-invasive method for predicting sudden cardiac death remains undetermined.
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Dronedarone is a new antiarrhythmic drug with structural similarities to amiodarone.
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The optimal timing of surgery for asymptomatic severe mitral valve regurgitation (MR) is unclear. Thus, Kang et al from South Korea studied the outcomes of patients treated with early surgery to those treated more conservatively in a prospective observational study.
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Efforts to decrease door-to-balloon time for primary percutaneous intervention (PCI) in an acute ST elevation myocardial infarction (STEMI), may include preferential triage to hospitals expert in primary PCI, partly because of evidence suggesting better outcomes.
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Revascularization, in conjunction with optimal medical therapy, remains a critical component in therapy for patients with obstructive coronary artery disease (CAD).
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Since the risk of gastrointestinal bleeding is increased when clopidogrel is added to aspirin therapy in patients with acute coronary syndromes (ACS), many prescribe proton-pump inhibitors (PPIs) to reduce this risk. However, mechanistic studies suggest that PPIs may reduce the effectiveness of clopidogrel.
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Utilizing genotyping for warfarin therapy in patients with non-valvular atrial fibrillation may not be cost-effective.
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A prospective study of men and women showed that duration of sleep is correlated with coronary artery calcification with 1 hour more of sleep daily reducing the odds of calcification over 5 years by 33%.