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A variety of highly effective agents for primary insomnia are currently available including benzodiazepines, benzodiazepine receptor agonists, and other classes. Agents that impact the benzodiazepine receptors (i.e., either benzodiazepines or benzodiazepine receptor agonists) are controlled substances and have occasional problematic issues such as misuse, diversion, cognitive clouding, and rebound upon withdrawal.
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In elderly patients hospitalized with heart failure and LVSD, beta-blocker use was clinically effective in reducing mortality and rehospitalization, but patients with preserved systolic function had poor outcomes and beta-blockers did not significantly influence the mortality and rehospitalization rate for these patients.
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Iloperidone is the newest atypical antipsychotic agent to be approved by the FDA. It is chemically similar to risperidone and ziprasidone. Vanda Pharmaceuticals will market iloperidone as Fanaptâ„¢.
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In patients with proximal deep vein thrombosis (DVT), tailoring the duration of oral anticoagulation based on serial ultrasonography reduces the rate of recurrent DVT. Prolongation of chronic anticoagulation may accelerate vein recanalization. Residual DVT on ultrasonography is a marker of hypercoagulability.
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For patients with chronic insomnia, sleeping pills in combination with cognitive behavioral therapy (CBT) resulted in improved sleep satisfaction during acute therapy, but long- term treatment was enhanced by stopping the medication and continuing only CBT.
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Acute pancreatitis was described by surgeon Berkely Moynihan in 1925 as " the most terrible of all calamities that occur in connection with the abdominal viscera." Although our understanding and management of this condition has progressed considerably since then, this description remains apt at least for the most advanced and complex cases of severe acute pancreatitis.
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Investigators at the University of Utah hospital carried out a comprehensive observational study of alarms that sounded in the medical ICU.
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The infection control technique of contact precautions is intended to prevent the spread of pathogens by airborne, droplet, or contact transmission.
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