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Prone positioning has been advocated as a management strategy for patients with acute respiratory distress syndrome (ARDS), but despite evidence of improved oxygenation with the technique, numerous studies have yet to establish a mortality benefit from the practice.
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In this issue: Statin and niacin increase HDL-C, omeprazole reduces effectiveness of clopidogrel, darbe-poetin increases risk of stroke, statins decrease risk of gallstone disease, FDA Actions.
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Early goal-directed therapy (EGDT) has been shown to reduce hospital mortality from severe sepsis and septic shock. Puskarich et al hypothesized that long-term outcome would also be improved.
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Irritable bowel syndrome symptoms can be treated effectively with soluble fiber such as Metamucil.
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Middle-age female health professionals at risk for cardiovascular disease and type 2 diabetes derived no benefit from more than 7 years of daily supplementation with a combination pill composed of folic acid, vitamin B6, and vitamin B12 designed to decrease serum levels of homocysteine.
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A meta-analysis was conducted of the incidence of side effects reported in randomized controlled trials of women taking phytoestrogens for the treatment of menopausal symptoms. Except for gastrointestinal side effects, women taking phytoestrogens were not at higher risk of side effects.
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Concerns over cell phones use and subsequent development of cancer, especially brain tumors, have occasionally dominated the news and helped create an entire business sector devoted to hands-free devices.
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A standardized extract of Tripterygium wilfordii Hook F root was compared with sulfasalazine therapy in subjects with active rheumatoid arthritis. After a 24-week intervention, those taking the botanical remedy experienced significantly greater progress both clinically and in laboratory assessments when compared with the sulfasalazine group, with improvements occurring rapidly. The findings are hampered somewhat by a significant dropout rate in both study groups.
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This single-group cohort before-and-after study of an intensive educational program for primary care physicians focusing on mindful communication and self-awareness demonstrated improvements in physician well-being and attitudes toward patient- centered care.