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The FDA has approved the first product for the treatment of Hunter syndrome. Idursulfase is a purified form of iduronate-2-sulfase, a 525-amino acid glycoprotein, produced by recombinant DNA technology.
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Treatment of Parkinson's disease with dopamine agonist medications may precipitate impulse-control disorders such as compulsive gambling, buying, and hypersexuality.
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A retrospective review of patient records representing preventive healthcare visits of women aged 50-69 revealed that gynecologists are more likely than family physicians or internists to follow breast cancer screening guidelines.
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A total of 2084 men from two Framingham Heart Study cohorts had endogenous levels of total serum estrogen, testosterone and dehydroepiandrosterone sulfate (DHEA-S) measured.
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In the case of fulminant meningococcal disease, laboratory tests are not available fast enough to be helpful, and may be within normal ranges early in a precipitous course. Provide rapid fluid support and antibiotics immediately and obtain blood cultures with the initial IV placement if possible, but do not delay antibiotics for the sake of good cultures.
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Among elderly persons without chronic kidney disease, cystatin C is a prognostic biomarker of risk for death, cardiovascular disease, and chronic kidney disease.
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Discontinuation of anticoagulation 3-6 months after successful atrial fibrillation ablation is reasonable in low-risk patients.
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Angiotensin-converting enzyme (ACE) inhibitors have been shown to reduce mortality and myocardial infarction (MI) in patients with heart failure due to reduced left ventricular (LV) systolic function.