Cardiology
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Thrombolysis vs. Surgery for Thrombosed Mechanical Prosthetic Valves
A study of patients with obstructive prosthetic valve thrombosis that deployed low-dose, slow infusion thrombolysis or surgery using shared decision-making, showed thrombolysis was highly effective and resulted in fewer major complications than surgery.
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Comparison of Treatments Highlights Poor Outcomes for TAVR Patients with Infective Endocarditis
In this analysis of a large registry of transcatheter aortic valve replacement patients with confirmed endocarditis, most were treated with antibiotics without surgery. In-hospital and one-year mortality rates were high and were not much better in patients who underwent surgery.
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Donepezil Transdermal Patch (Adlarity)
Donepezil transdermal system can be prescribed to treat mild, moderate, and severe dementia of the Alzheimer’s type.
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Bloodstream Infections During COVID-19
Severity of illness, prolonged hospital stays, use of mechanical ventilation, and use of immune-modulating agents in patients with COVID-19 may have contributed to observed increases in hospital-acquired blood stream infections and attendant mortality.
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Empower Patients With Education Resources About Pelvic Floor Disorders
Online patient resources for pelvic floor disorders on the American Urogynecologic Society patient portal are underused by women with pelvic floor disorders.
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Gastrointestinal Bleeding on Anticoagulants: Predicting Colorectal Cancer in Afib Patients
A large Danish registry study showed that in atrial fibrillation patients on oral anticoagulants and who experience a lower gastrointestinal bleed, the incidence of a subsequent diagnosis of colorectal cancer is significantly higher than in those without bleeding.
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The Effects of Diet, Nutrition, and Weight on Fibromyalgia
This review of evidence for the use of dietary interventions to treat fibromyalgia shows symptom reduction associated with a variety of healthy diets. Weight loss may be key to understanding this connection, but more research is needed.
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The Association Between Cancer Mortality and Physical Activity for Middle-Aged and Older Patients
In a prospective cohort study of 8,002 middle-age and older Black and white adults in the United States, replacing sedentary behavior with physical activity was associated with a lower cancer mortality risk.
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The Effects of Diet, Nutrition, and Weight on Fibromyalgia
A review of evidence for the use of dietary interventions in the treatment of fibromyalgia shows symptom reduction associated with a variety of healthy diets. Weight loss may be key to understanding this connection, but more research is needed.
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ED Providers Are Frequent Defendants in Aortic Pathology Malpractice Claims
Making the diagnosis is everything — to avoid patient injury and, ultimately, to avoid litigation.