Cardiology
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Anticoagulation Therapy in Octogenarians with Atrial Fibrillation
In patients age 80 years and older with atrial fibrillation who were not considered for oral anticoagulants because of serious comorbidities, one-quarter of the recommended daily dose of edoxaban was superior to placebo for preventing thromboembolic events.
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Outcomes of COVID-19-Associated Acute Myocarditis
In a review of COVID-19-associated acute myocarditis, investigators learned it is a rare complication that can occur without concomitant pneumonia, and frequently presents as cardiogenic shock. With supportive therapy, the short-term mortality rate is low.
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Sodium Restriction in Chronic, Stable Heart Failure Patients
A study of a low-sodium diet for chronic, stable heart failure patients after one year showed no difference in hard clinical outcomes, but the degree of sodium restriction was modest.
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Oral Anticoagulation Falls Short as Default Treatment Post-TAVR
In patients without an indication for anticoagulation undergoing transcatheter aortic valve replacement, treatment with edoxaban did not significantly affect the incidence of leaflet thrombosis as detected by CT scans.
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Panel Backs Away from Aspirin for Cardiovascular Disease Primary Prevention
Experts say patients age 60 years and older should not start taking the drug to prevent a first stroke or heart attack.
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Posterior Myocardial Infarction, or deWinter T Waves?
The ECG was taken from an older man who complained of chest pain over the past month. The pain severity was even worse on the day he underwent imaging. How would you interpret the ECG?
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Dexmedetomidine Sublingual Film (Igalmi)
Dexmedetomidine can be prescribed for the acute management of agitation associated with schizophrenia or bipolar I or II disorder.
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COVID-19 Vaccine and the Menstrual Cycle
In a retrospective cohort analysis of prospectively tracked menstrual cycle data from the smartphone application “Natural Cycles,” the COVID-19 vaccine was associated with a less than one day change in menstrual cycle length and no change in menses length.
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The Association Between Cancer Mortality and Physical Activity for Middle-Aged and Older Patients
In a prospective cohort study of older U.S. adults, replacing sedentary behavior with physical activity was associated with a lower cancer mortality risk.
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Postmenopausal Estrogen May Prevent Death from COVID-19 Infection
Swedish researchers found taking postmenopausal estrogen was associated with a lower death rate from COVID-19 infection. Taking estrogen suppression therapy for breast cancer was associated with a higher death rate compared with controls.