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In this issue: ACEI/ARB therapy for AS; safety alert issued for dronedarone; statins and cancer risk; nesiritide and heart failure; and FDA actions.
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Would you like to start a fight? Just ask a colleague how he or she selected the level of positive end-expiratory pressure (PEEP) for a patient.
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My hospital has a contract to provide medical care to the county jail. At any one time, there are more than 10,000 inmates in the county jail facilities supervised by the sheriff's office. We often see patients who are in custody and have sustained trauma, sometimes from less than lethal weapons. In my humble opinion, these devices reduce the risk of injury to the law enforcement officer when attempting to arrest or control a violent individual, and they greatly reduce the risk of serious injury or even death to the violent individuals themselves. However, even these less than lethal force weapons can cause significant damage when used at close range or on individuals with underlying medical conditions that render them vulnerable to the effects of these weapons.
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Intensivists experienced significantly less burnout, work-home life imbalance, and job distress under an interrupted schedule vs a continuous (half-month) schedule. ICU length of stay and mortality were non-significantly higher under continuous scheduling.
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In this study, the authors attempt to develop a risk stratification score to predict bleeding in patients treated with warfarin oral anticoagulation.
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High-dose loop diuretics are often necessary to reduce elevated filling pressures in patients with heart failure. However, they are known to activate neurohormonal mechanisms that may be harmful.
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Cardiac resynchronization therapy (CRT) is now accepted as a disease-modifying therapy in patients with heart failure, left ventricular dysfunction, and intraventricular conduction defects. In this paper, Sipahi and colleagues review the data on the benefits of CRT in relationship to baseline QRS duration.