Cardiology
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Clinical Briefs
In this issue: flat basal insulin, another possible interventional fix for atrial fibrillation, and a glimmer of hope for beta-blockers in heart failure from diastolic dysfunction.
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Tedizolid Phosphate Injection and Tablets (Sivextro®)
A new oxazolidinone-class antibacterial has been approved for the treatment of acute bacterial skin and skin structure infections.
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Prevalence of Rest Tremor in Essential Tremor
Rest tremor is seen in patients with more advanced essential tremor, yet its prevalence varies significantly between patient groups.
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Is It Time to Purge Full-Strength Aspirin from the Outpatient Armamentarium?
The current study provides further evidence of a lack of benefit to high-dose maintenance aspirin, along with a suggestion of harm.
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Comparative Efficacy and Safety of Blood Pressure-lowering Agents in Adults with Diabetes and Kidney Disease
Although no blood pressure-lowering strategy prolonged survival in adults with diabetes and kidney disease in this meta-analysis, angiotensin-converting enzyme and angiotensin-receptor blockers, alone or in combination, were the most effective pharmacological strategies to prevent the development of end-stage renal disease.
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Prevention of Proton Pump Inhibitor-induced Bowel Symptoms with Probiotics
The administration of a Lactobacillus paracasei strain (F19) twice daily and 3 times per week for 6 months appears to reduce the incidence of bowel symptoms (bloating and flatulence) and reduce changes in bowel habits (increased stool frequency and loose stools) but not abdominal pain in patients taking proton pump inhibitors.
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Sustainable 25(OH)D Levels? Choose Vitamin D3 over D2
Compared to vitamin D2, daily supplementation with vitamin D3 appears to sustain serum 25(OH)D levels even after discontinuation of supplementation in healthy adults.
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Spiritual Interventions for Patients with Cancer
A systematic meta-analysis investigating the effects of spiritual intervention in patients with cancer found that spiritual interventions had significant moderate effects on spiritual well-being, meaning of life, and depression.
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Integrative Therapies for Fibromyalgia – What News?
Although fibromyalgia remains a challenging management problem in clinical medicine, significant progress has been made in the last five years in terms of identifying underlying neurobiological abnormalities, which may one day elucidate the pathophysiology of the disorder.
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When Do Ventilator Modes Matter?
Although pressure-controlled ventilation and volume-controlled ventilation approach mechanical breath delivery differently in terms of inspiratory flow and airway pressure characteristics, this comprehensive review found no significant differences in terms of their impact on breathing mechanics or gas exchange in patients with various forms of acute respiratory failure.