Cardiology
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Antibiotics for Acute Appendicitis
Appendectomy has been the treatment for acute appendicitis since the late nineteenth century. During the past decade, the notion of treating acute appendicitis with antibiotics alone has been proposed and evaluated in several clinical trials. However, these trials have been criticized because of methodological limitations.
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Is Peripheral Intravenous Administration of Vasopressors Really Safe?
Vasoactive medications are most commonly administered through central venous catheters -
Emergent Vascular Access: Is Intraosseous Better Than Central Venous Catheter Placement?
Traditionally, the easiest vascular access has been placement of a triple lumen catheter in the femoral vein, as anatomic landmarks here are often easier to identify than other areas, minimizing the need for ultrasound assistance. -
Using Critical Care Ultrasonography to Diagnose the Etiology of Acute Respiratory Failure
Thoracic ultrasound and limited echocardiography may be useful to help differentiate the causes of acute hypoxic respiratory failure in the ICU.
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Optimal Duration of Anticoagulation for Unprovoked Pulmonary Embolism
Treatment for 24 months with oral anticoagulation for unprovoked, first-time pulmonary embolism was superior to treatment for 6 months only.
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The Complex Intersection of Critical and Palliative Care
Ventilator withdrawal with expected death is now considered an ethically and morally acceptable practice. Here's what you need to know.
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Clinical Briefs
In this section: Reconsidering the value of oral nutritional supplementation in patients admitted for COPD; recognizing a relationship between asthma and obesity; and weighing the benefits of sound stimulation in Alzheimer's patients.
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Eluxadoline Tablets (Viberzi) and Rifaximin (Xifaxan) Tablets
Both drugs appear to provide modest benefit in irritable bowel syndrome with diarrhea.
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Statin Use and Cognitive Effects: Not a Brain Drain
A meta-analysis of data from more than 28,000 patients enrolled in 18 randomized, placebo-controlled trials of statin therapy failed to show a causal relationship between treatment and adverse neurocognitive effects for patients with and without cognitive impairment.
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Prostate Cancer and Smoking: One More Reason to Trash the Tobacco
Study showed that following prostatectomy for cancer, smokers and ex-smokers had a higher risk of recurrence.