Cardiology
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Sacubitril and Valsartan Tablets (Entresto)
A new option for heart failure incorporates two drugs with different mechanisms of action.
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Antibiotics for Acute Appendicitis
A randomized, multicenter clinical trial compared antibiotic therapy to surgery for uncomplicated acute appendicitis and found most patients who received antibiotics did not require appendectomy during the 1-year follow-up period.
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Are Premature Ventricular Contractions Dangerous?
A higher frequency of premature ventricular contractions was associated with a decrease in left ventricular ejection fraction, an increase in incident congestive heart failure, and an increase in mortality.
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The Spice of (Prolonged) Life
ABSTRACT & COMMENTARY: Habitual consumption of spicy foods is associated with reduced mortality independent of other risk factors for death. Hot stuff!
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Music for Postoperative Pain
Music, irrespective of type and timing, improves recovery from surgical procedures based on this meta-analysis.
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Preventing Adolescent Metabolic Syndrome: A Lesson from Finland
Adolescent metabolic syndrome predicts type 2 diabetes mellitus and subclinical atherosclerosis in adulthood. This Finish study found that repeated infancy-onset dietary intervention primarily aimed at reducing intake of saturated fat from infancy to early adulthood was effective in preventing adolescent metabolic syndrome.
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Acupuncture and Alzheimer’s Disease: A Review of a Meta-Analysis
According to Zhou’s recent research, acupuncture is a safe option that may be effective at improving cognitive function in patients with Alzheimer’s disease when used in conjunction with certain pharmaceutical treatments.
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Integrative Therapies for Type 2 Diabetes Mellitus: Micronutrient Supplements
This article will focus on the role of micronutrients in the prevention and management of type 2 diabetes mellitus. Micronutrients, including vitamins and minerals, are required for many functions in the body, including glucose metabolism, insulin activity, and prevention of tissue oxidation. Unfortunately, chronic hyperglycemia has been shown to reduce the levels of various micronutrients in the body, which further disturbs glucose regulation and potentially worsens diabetic complications. Over the past few decades, researchers have examined the effects of supplementing these micronutrient deficiencies, and some of the most commonly encountered supplements in clinical practice are reviewed below.
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Does Bacteremia Associated with Bone and Joint Infections Require Prolonged IV Antibiotic Therapy?
Two hundred sixty-five previously healthy children with culture-proven acute bone or joint infection (age range 3 months to 15 years) were studied. -
A Modern Epidemiologic View of Status Epilepticus in the United States
Although definitions have changed, status epilepticus is presently defined as a prolonged seizure or multiple seizures with incomplete return to baseline function lasting longer than 5 minutes.