Cardiology
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Evolocumab Injection (Repatha)
Evolocumab is indicated as an adjunct to diet and maximally tolerated statin therapy for the treatment of heterozygous familial hypercholesterolemia or clinical atherosclerotic cardiovascular disease in patients who require additional lowering of LDL-C.
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Vitamin D and Diabetic Neuropathy
Vitamin D deficiency may exacerbate the clinical manifestations of diabetic neuropathy, and supplementation with vitamin D3 may be beneficial.
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Nutrition Therapy for Hypertension Using the Nitric Oxide Pathway
Daily one-time ingestion of inorganic nitrate from beet juice consistently lowered blood pressure in hypertensive patients by an amount comparable to single-drug therapy.
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Intensification of Oral Therapy for Type 2 Diabetes
ABSTRACT & COMMENTARY: It may not be relevant to primary care physicians. Here's why.
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Spice is Nice
The habitual consumption of spicy foods is associated with reduced mortality independent of other risk factors for death.
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N-acetylcysteine as Adjunctive Therapy for Therapy-resistant Tobacco Use Disorder
Tobacco cessation programs have variable success rates and often employ the use of multiple strategies, including behavioral counseling and pharmaceutical treatments. This study investigates the use of N-acetylcysteine in combination with group behavioral therapy as a treatment for tobacco use disorder resistant to first-line smoking cessation treatments.
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Omega-3s for the AREDS2 Cohort Are Not Beneficial for Preventing Cognitive Decline
A sub-analysis of the AREDS2 randomized, controlled trial that involved supplemental omega-3 fatty acids failed to find benefit on cognitive function over 5 years.
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Integrative Therapies for Type 2 Diabetes Mellitus: Botanical Supplements
This review will focus exclusively on the role of botanicals for treating type 2 diabetes mellitus. Only recently have rigorous research methods been applied to the study of botanical remedies.
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Serum Chloride Level Predicts Mortality in Acute Heart Failure
The association between serum sodium level and outcomes in acute decompensated heart failure is well-established.
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Community-acquired Pneumonia Requiring Hospitalization in Adults
An active population-based surveillance of community-acquired pneumonia requiring hospitalization in adults 18 years of age and older was conducted in five hospitals in Chicago and Nashville.