Cardiology
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Five-year EVEREST II Results Allay Long-term Safety and Durability Concerns About MitraClip
Although MitraClip patients had higher rates of re-operation in the first year, adverse event rates in the 1- to 5-year range were reassuringly low and were comparable with surgery.
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Selecting Patients for Statin Primary Prevention
The new vascular disease risk calculator discriminates who will experience a vascular event in the near future better than using a trial entry criteria approach or a hybrid approach.
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Blood Transfusion in Cardiac Disease Patients
In patients admitted to the ICU with comorbid cardiac disease, the hemoglobin level below which transfusion was associated with lower hospital mortality was < 8-9 g/dL and < 9-10 g/dL if the admitting diagnosis was acute myocardial infarction.
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Is Sodium Restriction Detrimental in Chronic Heart Failure?
Dietary sodium restriction may have a detrimental effect on outcome in patients with symptomatic chronic heart failure. They stress that a randomized clinical trial is warranted to resolve the issue.
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Acupuncture for Acute Low Back Pain in the Emergency Department
Acupuncture may reduce acute low back pain among patients treated in the emergency department.
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Yoga for Prenatal Depression
Yoga therapy reduces levels of prenatal depression compared to non-pharmacological treatment programs not involving yoga therapy. Yoga therapy integrating meditation and relaxation practice improve depression levels more than exercise-only yoga therapy.
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Eat Less Sugar: The New National Dietary Guidelines
The 2015-2020 Dietary Guidelines for Americans introduces a new recommendation that added sugar should be limited to no more than 10% of total calories.
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Antioxidant Therapies: A Contraindication for Melanoma?
A series of experiments utilizing human melanoma cells found that oxidative stress was higher in circulating melanoma cells and distant metastasis than the original subcutaneous tumors, suggesting a higher oxidative stress burden subsequent to leaving the original tumor environment. Treatment of animals or tumor cell lines with antioxidants led to increased metastasic burden.
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Exercise for Depression During Pregnancy
Exercise is associated with better mental outcomes during pregnancy.
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Non-seasonal Major Depressive Disorder: Bright Light Therapy and/or Fluoxetine
In this four-pronged study comparing the effect of bright light treatment, fluoxetine, a combination of these two interventions, and placebo in patients with major depressive disorder, the combination treatment appears the most consistently effective.