Cardiology
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Is Screening for Atrial Fibrillation Cost Effective?
Self-screening for atrial fibrillation in elderly individuals could lead to lower stroke rates, prevent bleeding-related hospitalizations, and save money.
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Is It Better to Up-Titrate Medications Faster in Acute Heart Failure Patients?
Early intensive up-titration of guideline-recommended therapy in patients admitted for heart failure reduced 180-day readmission and all-cause mortality at the cost of more adverse events (but not serious or fatal ones).
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Triglyceride-Lowering Therapy and Cardiovascular Events
Researchers studied pemafibrate vs. placebo in patients with type 2 diabetes, mild-to-moderate triglyceride elevations, and low levels of HDL and well-controlled LDL cholesterol. Despite a 31% reduction in triglyceride levels, there was no improvement in the risk of cardiovascular outcomes over a median follow-up of 3.4 years.
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Mitral Transcatheter Edge-to-Edge Repair Gains Traction in Cardiogenic Shock Patients
The authors of this large registry study examined transcatheter edge-to-edge repair in patients with cardiogenic shock and severe mitral regurgitation (MR). Successful repair was achievable in most patients and was associated with lower mortality rates and heart failure hospitalization at one year.
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The Clue in Lead II
How should one interpret the ECG in the figure? The figure was obtained from a 40-year-old man who was hemodynamically stable at the time this tracing was recorded. The key clue is in lead II.
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Periodontal Disease as an Independent Risk Factor for Cardiovascular Disease
Researchers used data from the 2013 to 2014 period of the National Health and Nutrition Examination Survey to study possible connections between poor oral health and the likelihood of developing cardiovascular disease.
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Is Illicit Substances Use Associated with Atrial Fibrillation?
An observational study of a huge cohort of patients admitted to California hospitals showed patients who used cocaine, methamphetamine, opiates, and cannabis were at a higher risk of developing atrial fibrillation vs. those with similar risk factors who did not use the substances.
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The Right Dose at the Right Time: Improving Hypertension Outcomes
An online study of evening vs. morning administration of patients’ usual antihypertensive medications, with a median five-year follow-up, revealed there is no difference in major cardiovascular outcomes between the two periods.
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Just How Good is ‘Good’ Cholesterol?
Investigators challenge high-density lipoprotein levels as the standard for predicting cardiovascular disease risk.
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Persistent Asthma Patients Show More Plaque Buildup, Inflammation
Pulmonary ailment could speed carotid artery damage, create more inflammatory biomarkers.