Cardiology
RSSArticles
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CABG Improves Long-term Survival in Severe Left Ventricular Dysfunction
In patients with coronary artery disease, heart failure, and left ventricular ejection fraction < 35%, coronary artery bypass grafting plus medical therapy was associated with improved survival compared to medical therapy alone.
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TAVR in Intermediate-risk Patients: How Low Can We Go?
Transcatheter and surgical aortic valve replacement in an intermediate-risk population have similar rates of death and disabling stroke at two years.
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Clinical Briefs
In this section: examining autoimmune disorders associated with vitiligo; moderate alcohol consumption is not associated with reduced all-cause mortality; and rethinking the American diet.
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Ixekizumab Injection (Taltz)
Ixekizumab is indicated for the treatment of adults with moderate-to-severe plaque psoriasis who are candidates for systemic therapy or phototherapy.
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Outcome of PCSK9 Inhibitor-treated Patients
In a meta-analysis of 17 studies, proprotein convertase subtilisin-kexin type 9 serine protease inhibitors markedly reduced low-density lipoprotein cholesterol levels and all-cause mortality, but was associated with a significant increase in neurocognitive adverse events.
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Menopausal Hormone Therapy: Useful and Indicated for Vasomotor Symptoms
Menopausal hormone therapy is the most effective treatment for symptoms of the menopause, and benefits may exceed risks for most women within 10 years of menopause.
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Drug-resistant Hypertension? Consider Adding a Nonpharmacologic Prescription
In patients with obstructive sleep apnea and hypertension, continuous positive airway pressure use was associated with clinically and statistically significant reductions in blood pressure for both resistant and non-resistant hypertension.
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Chest Pain and Giant T Wave Inversion
Chest pain (rather than shortness of breath) and ST elevation (rather than T wave inversion) in leads V1 and V2 make massive pulmonary embolism unlikely.
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Clinical Briefs
In this section: the insulin misadministration problem; comparing smoking cessation pharmacotherapies; more support for ambulatory BP monitoring.
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Tenofovir Alafenamide vs Tenofovir Disoproxil Fumarate
Tenofovir alafenamide has replaced the tenofovir disoproxil fumarate component of two commonly used drug combinations for HIV-1 infection.