Cardiology
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Can a Brain Condition Affect the Heart?
A large, prospective cohort study in women with more than two decades of follow-up indicated a consistent link between migraine and cardiovascular disease events, including cardiovascular mortality.
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Cerebral Microbleeds: Risk Factor for Symptomatic Intracerebral Hemorrhage
Cerebral microbleeds (CMBs), as visualized on gradient-echo or susceptibility-weighted MRI, are considered markers of bleeding-prone cerebral microvessels and constitute a significant and independent predictor of future intracerebral hemorrhage. -
Buprenorphine Implant for Subdermal Administration (Probuphine)
The FDA has approved the first buprenorphine implant for the treatment of opioid dependence. Buprenorphine is a partial agonist at the mu-opioid receptor and an antagonist at the kappa-opioid receptor. Buprenorphine was previously approved as oral and sublingual tablets. The implant is marketed as Probuphine.
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Human Adenovirus B7: Severe Infection
ABSTRACT & COMMENTARY: Patients with HAdV-B7 were more likely to be adults and to have longer hospital stays.
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Dual Antiplatelet Therapy Appears More Effective Than Single Therapy
The CHANCE study showed that the combination of aspirin and clopidogrel was superior to aspirin alone for reducing the risk of stroke in the first 90 days after a TIA or minor ischemic stroke (N Engl J Med 2013;369:11-19). -
Can Procalcitonin Predict Need for ICU Admission in Community-acquired Pneumonia Patients?
Several studies have focused on the use of procalcitonin in diagnosing sepsis, as a prognostic marker in sepsis, and as a guide to antibiotic decisions in sepsis.
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Nature Nurturing Health
A national prospective cohort study of nurses found that higher levels of green vegetation were associated with decreased mortality.
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Seafood Consumption and Brain Mercury Levels in Older Adults with Dementia
This cross-sectional study of older adults who were part of the Rush Memory and Aging Project demonstrated that moderate seafood consumption was correlated with a decreased level of brain Alzheimer’s disease neuropathology in APOE ε4 carriers. Higher brain levels of mercury were correlated with higher seafood consumption. However, these levels were not correlated with brain neuropathology.
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Individualized Integrative Medicine Treatment for Preoperative Anxiety
In a randomized, clinical trial investigating the treatment of preoperative anxiety, standard sedating medication with a specified add-on individualized integrative technique is the most effective intervention.
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Olive Oil or Mixed Nuts Consumption, as Part of the Mediterranean Diet, May Help Reduce Body Weight and Central Adiposity
The long-term vegetable fat enrichment of a Mediterranean diet leads to less weight gain and less increase of central adiposity than a control diet.