Cardiology
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Poor Cardiovascular Health a Predictor for Premature Brain Aging
Worse cardiovascular health at age 36 years can predict worse brain aging and associated cognitive problems later in life.
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New Therapy for Resistant Hypertension
Aprocitentan demonstrated efficacy for additional therapy beyond standard multidrug treatment in resistant hypertension.
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Is It Better to Up-Titrate Medications Faster in Acute Heart Failure Patients?
Early intensive up-titration of guideline-recommended therapy in patients admitted for heart failure reduced 180-day readmission and all-cause mortality rates at the cost of more adverse events (but not serious or fatal ones).
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Low-Fat vs. Mediterranean Diet for Secondary Prevention
A study of stable coronary heart disease patients comparing the Mediterranean diet to a low-fat diet over a seven-year follow-up showed the Mediterranean diet was superior at preventing major cardiovascular events.
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Providing Ethical Neonatal Cardiac Care
The complexities associated with neonates with cardiac disease require a collaborative and cohesive strategy. Shared decision-making, research ethics, and outcomes reporting are important considerations.
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Researchers Find Little Difference in Efficacy Between Top Heart Failure Treatments
In a head-to-head comparison of furosemide and torsemide, one diuretic was not significantly more efficacious than the other in improving heart failure survival rates.
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An Easy Measure of Potentially Harmful Salt Intake
Those who rarely or never added salt to their food and strongly adhered to the Dietary Approaches to Stop Hypertension diet exhibited the lowest incidence of subsequent cardiovascular disease.
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Is Chlorthalidone Superior to Hydrochlorothiazide for Treating Hypertension?
Randomly switching half of patients with hypertension on hydrochlorothiazide to chlorthalidone did not produce any difference in major cardiovascular outcomes.
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Ablation vs. Drug Therapy for Atrial Fibrillation, Revisited
A three-year follow-up of EARLY-AF, a study of relatively young and healthy patients with recent atrial fibrillation, showed cryoablation remains superior to drug therapy for preventing the development of persistent atrial fibrillation.
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Outcomes for Patients Undergoing Transcatheter Edge-to-Edge Repair for Functional Mitral Regurgitation
Researchers analyzed transcutaneous mitral valve repair in patients with moderate-to-severe or worse mitral valve regurgitation caused by cardiomyopathy and heart failure despite maximally tolerated guideline-directed medical therapy. Compared to medical therapy alone, undergoing repair resulted in fewer heart failure and other cardiovascular disease hospitalizations and significantly more time free of hospitalization and death.