Cardiology
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Health Benefits of Turning ‘Bus Drivers’ into Conductors
A large meta-analysis including data from more than one million subjects and 16 studies revealed that specified levels of moderate-intensity physical activity can significantly lessen the health risks of sedentary lifestyles.
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Therapeutic Touch for Cancer Pain: An RCT
In a study of 90 men with cancer-related pain, the arm receiving seven sessions of therapeutic touch derived more benefit than a placebo group or a control arm of no intervention.
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Noninvasive Ventilation in Asthma Exacerbation: Predictors of Use and Outcomes
In this large, retrospective cohort study, the use of noninvasive ventilation (NIV) as an initial mode of ventilation for patients with asthma exacerbation was common; those successfully treated with NIV experienced lower inpatient mortality and shorter lengths of stay, but were likely a carefully selected population.
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Noninvasive Ventilation Delivered Via Helmet May Decrease Intubation Rates in Acute Respiratory Distress Syndrome
In this single-center, randomized, clinical trial, among patients suffering from acute respiratory distress syndrome, the use of helmet noninvasive ventilation was associated with a reduction in intubation rates, ICU length of stay, and hospital and 90-day mortality.
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Noninvasive Positive Pressure Ventilation in Acute Respiratory Failure
A summary of data supporting the use of noninvasive positive pressure ventilation and continuous positive airway pressure in the setting of acute hypoxic and hypercapnic respiratory failure.
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Heart Failure with Recovered Ejection Fraction: A Distinct Phenotype
Patients suffering from systolic heart failure who subsequently improve their ejection fraction experience a more favorable clinical course compared to those presenting with persistently reduced ejection fraction or heart failure with preserved ejection fraction.
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Hypothyroidism and PCI Outcomes
Hypothyroidism is common in patients undergoing percutaneous coronary interventions in a multivariate adjusted observational study was associated with worse long-term outcomes.
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Optimal Blood Pressure in Patients Presenting with Aortic Stenosis
A post-hoc analysis of patients suffering from mild to moderate aortic stenosis in a study of low-density lipoprotein cholesterol lowering showed that the optimal blood pressure for the best survival was 130-139/70-90 mmHg.
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An Important Update in the Bare-metal vs. Drug-eluting Stent Debate
This randomized trial showed no difference between contemporary drug-eluting stents and bare-metal stents with regard to death and myocardial infarction, while drug-eluting stents demonstrated an advantage in both repeat revascularization and stent thrombosis at six years of follow-up.
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Has the Benefit of Prophylactic ICDs Been Overestimated Among Those Suffering From Nonischemic Cardiomyopathy?
Prophylactic implantable cardioverter defibrillator implantation does not provide mortality benefit for nonischemic heart failure patients.