Cardiology
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A Prospective, Randomized Comparison of Video and Direct Laryngoscopy
In the largest prospective, randomized trial to date, use of video laryngoscopy improved glottic visualization but did not increase procedural success or decrease complications compared to direct laryngoscopy in medical ICU patients.
Early Initiation of Continuous Renal Replacement Therapy May Reduce Mortality in Patients Who Require Dialysis
Initiation of continuous renal replacement therapy for patients with Kidney Disease: Improving Global Outcomes stage 2 renal failure reduced 90-day all-cause mortality.
High-flow Nasal Cannula vs. Noninvasive Ventilation in Postextubation Failure
SYNOPSIS: In this multicenter, randomized, clinical trial of critically ill adults at high risk for reintubation, high-flow conditioned oxygen therapy was not inferior to noninvasive mechanical ventilation with regard to preventing reintubation and postextubation respiratory failure within 72 hours of extubation.
Diastolic Blood Pressure Goals
SYNOPSIS: An analysis of the community-based ARIC study showed that low diastolic blood pressures were associated with higher baseline and subsequent troponin T levels and adverse cardiac events, but not stroke.
Pulmonary Embolism Common Cause for Syncope in Hospitalized Patients
Syncope is a chief complaint for which neurologists often are consulted. In most cases, the neurological concern is possible stroke or an epileptic seizure. However, a variety of cardiopulmonary problems are most often the underlying cause of syncope, including cardiac arrhythmias and pulmonary embolism. The investigators of this study reviewed the clinical records of 560 patients (mean age of 76 years) who were admitted to the hospital with syncope.
New Paradigm in the Management of Massive and Submassive Pulmonary Embolism
SYNOPSIS: A multidisciplinary pulmonary embolism response team is a sustainable option to improve care for severe pulmonary embolism.
VRE and MRSA: Should We Stop Routine Contact Precautions?
SYNOPSIS: The value of routine contact precautions for VRE and MRSA is strongly challenged.
Do the Benefits of a Bioabsorbable Coronary Scaffold Also Disappear Over Time?
In the longest-term randomized, controlled study of coronary bioresorbable vascular scaffolds to date, the Absorb bioresorbable vascular scaffold was outperformed by its metallic drug-eluting stent counterpart.
Ablation of the Left Atrial Appendage for Long-standing, Persistent Atrial Fibrillation
Addition of left atrial appendage ablation to pulmonary vein isolation, and extensive other ablation, improved freedom from atrial arrhythmias in patients with long-standing persistent atrial fibrillation without increasing complications.
Sacubitril/Valsartan Associated with Reduced Risk of Hyperkalemia
In a secondary analysis of the PARADIGM-HF trial, the risk of severe hyperkalemia in heart failure patients taking a mineralocorticoid receptor antagonist was lower among patients treated with sacubitril/valsartan compared to those receiving enalapril.