Cardiology
RSSArticles
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MitraClip Experience in Functional Mitral Regurgitation
A post-regulatory approval, observational study of patients with symptomatic functional mitral regurgitation stratified by baseline left ventricular ejection fraction (LVEF) showed that these patients received substantial benefit at low rates of hospital mortality and other adverse events, regardless of baseline LVEF.
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Left Main Confusion: Two Randomized Trials Reach Seemingly Opposite Conclusions
The NOBLE and EXCEL trials randomized patients presenting with left main disease to treatment with percutaneous coronary intervention or coronary artery bypass graft.
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Spironolactone Improves Exercise Capacity in Diastolic Heart Failure
In a small randomized, controlled trial of patients presenting with heart failure with preserved ejection fraction, treatment with spironolactone was associated with improved exercise capacity and less exercise-induced increase in left ventricular filling pressures.
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High-flow Nasal Cannula vs. Noninvasive Ventilation in Postextubation Failure: Does It Matter?
In this multicenter, randomized, clinical trial of critically ill adults at high risk for reintubation, high-flow conditioned oxygen therapy was not inferior to noninvasive mechanical ventilation with regard to preventing reintubation and postextubation respiratory failure within 72 hours of extubation.
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Should We Use Non-invasive Ventilation to Treat Acute Respiratory Distress Syndrome?
Managing acute respiratory distress syndrome (ARDS) with non-invasive ventilation was associated with increased failure as the severity of ARDS increased.
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Rehabilitation in the ICU: More Questions Than Answers
In patients with acute respiratory failure, standardized rehabilitation therapy consisting of passive range of motion, physical therapy, and progressive resistance exercise did not decrease hospital length of stay compared to usual care.
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A New Paradigm in the Management of Massive and Submassive Pulmonary Embolism
A multidisciplinary pulmonary embolism (PE) response team is a sustainable option to improve care for severe PE.
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Clinical Briefs
In this section: treating refractory chronic pruritus, accelerating weight loss with technology, and lowering uric acid in gout patients.
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Eteplirsen Injection (Exondys 51)
Eteplirsen is indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients who present with confirmed mutation of the DMD gene that is amenable to exon 51 skipping.
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Warning: Reactivation of Hepatitis B Virus Coinfection During Treatment of Chronic Hepatitis C Virus Infection
Prior to initiation of hepatitis C virus treatment with direct-acting antivirals, patients should be screened for hepatitis B virus coinfection.