Cardiology
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Can Echo/Doppler Accurately Estimate LVEDP in Pulmonary Hypertension Patients?
In patients with pulmonary hypertension evaluated in a specialty clinic, echo/Doppler estimation of left ventricular end-diastolic pressure is not reliable for the determination of pre- vs. post-capillary pulmonary hypertension.
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Cardiac Resynchronization Therapy Reduces New Onset Ventricular Arrhythmias
In an analysis of the landmark Resynchronization in Ambulatory Heart Failure Trial, patients without prior ventricular arrhythmias randomized to cardiac resynchronization therapy experienced significantly less new onset ventricular arrhythmias than those randomized to implantable cardioverter defibrillator alone.
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Predicting Electrical Cardioversion Failure
A study of the 30-day success rate of electrical cardioversion of acute atrial fibrillation revealed five clinical predictors of recurrence.
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Complete vs. Infarct-related, Artery-only Revascularization in STEMI
Researchers randomized patients with ST elevation myocardial infarction and at least one noninfarct artery with angiographically significant stenosis to either fractional flow-reserve-guided complete revascularization by percutaneous coronary intervention or to no revascularization of noninfarct arteries.
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Clinical Briefs
In this section: a connection between atopic dermatitis and autoimmune disorders; association of sickle cell trait with hemoglobin; and the continuing search for dementia triggers.
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Naldemedine Tablets (Symproic) C-II
Naldemedine is indicated for the treatment of opioid-induced constipation in adults with chronic noncancer pain.
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Vitamin D to Prevent Acute Respiratory Infections?
Vitamin D supplementation is associated with a decreased risk of respiratory infections, especially in those who had low circulating levels of 25-hydroxyvitamin D.
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Migraine: Differences Between Males and Females
Hormonal and genetic differences factor into a greater prevalence and disability burden of migraine in teenaged girls and women; however, migraine is underdiagnosed and inadequately treated in boys and men.
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Troponin Highly Prognostic in Decompensated Heart Failure With Preserved Ejection Fraction
Among patients with acute decompensated heart failure and preserved ejection fraction, elevated troponin is associated with worse in-hospital outcomes and long-term survival, independent of other predictors.
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Is Exposure to Arterial Hyperoxia During Critical Illness Dangerous?
Exposure to severe hyperoxia during critical illness is associated positively with increased ICU and hospital mortality and associated negatively with ventilator-free days.