Cardiology
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Alcohol Septal Ablation in Younger HCM Patients: Should We Relax Guidelines?
Current guidelines recommend surgical myectomy over septal ablation for younger hypertrophic cardiomyopathy patients. A new study bridges part of the data gap, showing safety and efficacy of the procedure in young patients.
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Early Diuretic Administration Associated With Improved Survival in Acute Heart Failure Patients
Among patients presenting to the ED with acute heart failure, those who received the first dose of intravenous furosemide within 60 minutes of arrival demonstrated lower in-hospital mortality compared to those receiving the first dose after 60 minutes.
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Prevention of Myocardial Infarction in Atrial Fibrillation Patients
A large observational study showed that the primary prevention of myocardial infarction and stroke in patients with atrial fibrillation is better with vitamin K antagonists alone as compared to aspirin alone and dual therapy.
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Requiem for Beta-blockers Post-Myocardial Infarction?
A propensity score analysis of all hospital survivors of acute myocardial infarction in the United Kingdom from 2007-2013 showed that one-year survival in hospital patients without heart failure or left ventricular dysfunction treated with beta-blockers did not differ from survival in those patients not so treated.
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Clinical Briefs
In this section: Use caution with a nocturia treatment; an analysis of a cellulitis remedy; and handling influenza patients.
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Sarilumab Injection (Kevzara)
Sarilumab is indicated for the treatment of adults with moderately to severely active rheumatoid arthritis who have demonstrated an inadequate response or intolerance to one or more disease-modifying antirheumatic drugs.
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Possible Benefit From Pharmaceutical-grade Chondroitin on Knee Osteoarthritis
The authors of a European study found a statistically significant and clinically marginally significant reduction in pain at three and six months in patients taking pharmaceutical-grade chondroitin sulfate for knee osteoarthritis.
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Glucose Self-monitoring May Not Be That Useful
Researchers could not find any statistically significant differences in glycemic control or health-related quality of life between patients who performed glucose self-monitoring compared with those who did not.
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Early Hot Flashes Could Signal Increased Risk for Heart Disease
Women 42-55 years of age who experience hot flashes are more likely to exhibit poor vascular function.
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Is This a Typical Flutter?
Atrial flutter is characterized by a special pattern of regular atrial activity that in adults almost always occurs at a rate of 300/minute (250-350/minute range).