Cardiology
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Functional Outcomes After Receiving Life-sustaining Therapy in the ICU
Among patients who have spent at least three days in an ICU and required even brief mechanical ventilation and/or vasopressor support, almost half are dead and only one-third return to their baseline at six months. Several factors present on the first day of admission are associated with not returning to baseline status.
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Thrombocytopenia in the Critically Ill
Thrombocytopenia is not only a pathologic entity, but the severity of thrombocytopenia and the recovery time of the platelets often predicts outcome, including overall mortality of ICU patients. Critically ill patients with moderate and severe thrombocytopenia demonstrate higher ICU and hospital mortality. If the recovery is delayed beyond day four, several studies have demonstrated higher morbidity and mortality.
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Atrial Flutter or Atrial Tachycardia?
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Clinical Briefs
In this section: nonsteroidal anti-inflammatory drugs and gastrointestinal bleeding; rheumatoid arthritis; and community-acquired pneumonia.
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Delafloxacin Tablets (Baxdela)
Delafloxacin is indicated for the treatment of acute bacterial skin and skin structure infections caused by susceptible organisms.
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Atypical Transient Symptoms Require Aggressive Investigation for Cause
Atypical transient symptoms, such as partial sensory deficit, dysarthria, vertigo and unsteadiness, unusual visual deficits, and diplopia, usually are not classified as transient ischemic attacks, and they frequently are not investigated in the same fashion.
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Glycemic Measures May Vary Depending on Race
In patients with type 1 diabetes, hemoglobin A1c levels overestimate the mean glucose concentration in black persons compared with white persons, possibly owing to racial differences in the glycation of hemoglobin.
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Long-term Use of Proton Pump Inhibitors and Earlier Death
An observational study of a Veterans Affairs population showed that the use of proton pump inhibitors over a median 5.7-year follow-up period increased the risk of death by 25% compared with the use of histamine 2 blockers or no medication.
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Prevalence of Coronary Atherosclerosis in Indigenous South American Tsimané
Tsimané, a population living in the Bolivian Amazon, have the lowest prevalence of coronary artery disease among any population studied; individuals ≥ 40 years of age have mean low-density lipoprotein and high-density lipoprotein of 91 mg/dL and 39.5 mg/dL, respectively, despite a high inflammatory burden from parasites and pathogens.
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Yoga for Lumbago?
A review of randomized, controlled trials of treatments for chronic non-specific, low back pain revealed that yoga provides improvements in back-related function compared to non-exercise controls at intermediate time points, and in pain scores in the short term. Also, yoga seems to be comparable to exercise interventions, although the quality of evidence was low enough to preclude us from knowing for sure.