Cardiology
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Omega-3 Polyunsaturated Fatty Acid Supplementation and Cognitive Decline
As the first large randomized, placebo-controlled trial studying the efficacy of a lifestyle intervention with a nutraceutical compound (polyunsaturated fatty acid), the Multidomain Alzheimer Preventive Trial is a landmark study.
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B-type Natriuretic Peptide Is Less Useful in Elderly Patients With Dyspnea
Among patients ≥ 80 years of age presenting with acute dyspnea, B-type natriuretic peptide level was not useful for differentiating cardiac vs. respiratory etiologies when added to a model of clinical predictors.
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Advance Care Planning Must Advance Forward
Advance care planning is a continual process of preparing for future medical care in case patients are unable to make his or her own decisions. It includes engaging patients and families to reflect on patients’ personal goals, values, and belief systems, which ultimately translate into informing medical care. This process helps prepare the patient for current and future decisions regarding medical treatment. Data show that Americans have fallen behind on this process.
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Failure to Wean From the Ventilator: Is Pleural Effusion the Culprit?
The authors of a multicenter, prospective cohort study did not find an association between the presence of moderate or large pleural effusion and ventilator weaning failure.
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Functional Outcomes After Receiving Life-sustaining Therapy in the ICU
Among patients who have spent at least three days in an ICU and required even brief mechanical ventilation and/or vasopressor support, almost half are dead and only one-third return to their baseline at six months. Several factors present on the first day of admission are associated with not returning to baseline status.
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Thrombocytopenia in the Critically Ill
Thrombocytopenia is not only a pathologic entity, but the severity of thrombocytopenia and the recovery time of the platelets often predicts outcome, including overall mortality of ICU patients. Critically ill patients with moderate and severe thrombocytopenia demonstrate higher ICU and hospital mortality. If the recovery is delayed beyond day four, several studies have demonstrated higher morbidity and mortality.
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Atrial Flutter or Atrial Tachycardia?
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Clinical Briefs
In this section: nonsteroidal anti-inflammatory drugs and gastrointestinal bleeding; rheumatoid arthritis; and community-acquired pneumonia.
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Delafloxacin Tablets (Baxdela)
Delafloxacin is indicated for the treatment of acute bacterial skin and skin structure infections caused by susceptible organisms.
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Atypical Transient Symptoms Require Aggressive Investigation for Cause
Atypical transient symptoms, such as partial sensory deficit, dysarthria, vertigo and unsteadiness, unusual visual deficits, and diplopia, usually are not classified as transient ischemic attacks, and they frequently are not investigated in the same fashion.