Cardiology
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Clinical Briefs
In this section: treating hypothyroidism in seniors; revisiting penicillin allergies; and new diverticulitis guidance.
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Sofosbuvir, Velpatasvir, and Voxilaprevir Tablets (Vosevi)
Vosevi is indicated for the treatment of adult patients with chronic hepatitis C infection without cirrhosis or with compensated cirrhosis who are infected with genotype 1, 2, 3, 4, 5, or 6, and have been treated previously with a hepatitis C regimen containing an NS5A inhibitor.
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Eat Right, and Live
An improvement in diet over 12 years in middle-aged nurses and other health professionals resulted in a decreased risk of death.
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Glucose Self-monitoring Not Helpful for Non-insulin-treated Type 2 Diabetes
In this pragmatic randomized trial, self-monitoring blood glucose did not lead to lower hemoglobin A1c levels or improvement in health-related quality-of-life measures.
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Capsaicin for Painful Diabetic Peripheral Neuropathy
An 8% capsaicin patch relieves pain and improves sleep in patients with painful diabetic peripheral neuropathy.
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Helping Women at Risk for Breast Cancer to Exercise More and Lose Weight
A web- and phone-based intervention led to significant weight loss and a modest increase in moderate-to-vigorous activity in women at risk of breast cancer.
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High-intensity Interval Training in Older and Younger Adults
High-intensity interval training performed over 12 weeks reversed age-related differences of mitochondrial proteins in adults 65 to 80 years of age, as well as increased insulin sensitivity and VO2 peak, and decreased fat free mass in adults 18 to 30 years of age and 65 to 80 years of age.
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Active Children: Do Higher Levels of Activity Help Prevent Depression?
This prospective study found moderate to vigorous physical activity in early childhood correlated with a decreased number of depressive symptoms in later years.
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Does Celecoxib Pose Greater Cardiovascular Risks Than NSAIDs?
A controlled trial that included patients with arthritis on nonsteroidal anti-inflammatory drug (NSAID) therapy who were randomized to continuing NSAIDs or switching to celecoxib showed that cardiovascular and gastrointestinal event rates are low and not different on the two therapies.
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Palliative Care-based Intervention Improves Quality of Life in Chronic Heart Failure
Among patients with advanced heart failure, implementation of an interdisciplinary palliative care intervention was associated with improved quality of life.