Cardiology
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Irritable Bowel Syndrome, Constipation, and Quality of Life in Women
Irritable bowel syndrome has a negative effect on women’s quality of life and affects one-third of women who present for care with fecal incontinence.
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Antibiotics and Adverse Events: Doctors, Do No Harm
A retrospective study found that among 1,488 hospitalized patients who received an antibiotic, 298 experienced at least one antibiotic-associated adverse drug event. Furthermore, 287 of the antibiotic regimens were not clinically indicated, and 56 of these were associated with an adverse drug event.
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Are Right-sided Leads Needed?
The ECG in the figure was obtained from a man in his 50s who presented with new severe chest pain. How would you interpret this tracing? What area(s) of the heart are involved? What is the likely culprit artery?
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Clinical Briefs
In this section: opioid-induced nausea; considering the safety of proton pump inhibitors; and life after bariatric surgery.
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Secnidazole Oral Granules (Solosec)
Secnidazole is indicated for the treatment of bacterial vaginosis in adult women.
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Oily Fish Is Associated With Better Sleep
A study in Ecuador showed a strong positive correlation between dietary oily fish intake and sleep quality.
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A Rivaroxaban/Daily Low-dose Aspirin Combination and Cardiovascular Events
The addition of rivaroxaban to daily low-dose aspirin resulted in fewer cardiovascular outcomes and increased major bleeding compared to aspirin alone in patients with stable cardiovascular disease.
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A Cup of Coffee May Help Patients Live Longer
In a prospective cohort of patients coinfected with HIV and hepatitis C virus, drinking three or more cups of coffee per day halved the all-cause mortality risk.
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Spiritual Healing: A Randomized Clinical Trial
A randomized, controlled trial evaluated the effectiveness of Brazilian energy therapy — Spiritist “passé” — in multiple conditions associated with recovery in cardiovascular inpatients.
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Vitamin D and Colorectal Cancer: The Plot Thickens
In a follow-up study, researchers investigated whether single nucleotide polymorphism (SNP) genotypes in the vitamin D and calcium pathways are associated with the authors’ previous findings that daily intake of 1,000 IU vitamin D3 and/or 1,200 mg calcium did not reduce colorectal adenoma risk. The authors concluded that vitamin D3 supplementation benefits in the prevention of advanced colorectal adenomas may vary depending on vitamin D receptor genotype status.