Cardiology
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Topical Cannabis for Wound Pain: A Case Series
For three people with continued pain despite conventional treatment for pyoderma gangrenosum, topical cannabis led to statistically significant pain relief for two of them.
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Low Serum 25-hydroxyvitamin D and Risk of Frequent Headache
Low vitamin D levels are associated with a range of neurovascular diseases, but little data are available on the association between vitamin D levels and headaches. This retrospective, cross-sectional study showed that low serum vitamin D levels were associated with a higher risk of frequent headaches in middle-aged/elderly Finnish men.
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Black seed (Nigella sativa) for Asthma: Minimal Effects
SYNOPSIS: Black seed, crushed, in capsule form, administered to 76 people with asthma in a single-blind, randomized study, showed some minimal improvements in some, but not all, components of spirometry and one serum cytokine after 12 weeks.
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Use of Essential Oils as an Alternative Treatment for Depression
The antidepressant effects of essential oils are promising, but more studies in humans beyond preliminary stages are needed.
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Tai Chi and Fall Risk
Tai chi practice in the older and at-risk population reduces the risk of falls (with the most robust results in the short-term) and may reduce the risk of injury from falls; no effect is seen when measuring time to the first fall.
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Do Antibiotics Reduce Hormonal Contraceptive Effectiveness?
This is a systematic review of studies evaluating the effect of concomitant non-rifamycin antibiotics use on hormonal contraceptive effectiveness. Although data are limited, there is no evidence to support the existence of drug interactions.
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Patent Foramen Ovale Intervention Rises to Occasion in Cryptogenic Stroke
After years of uncertainty, three large randomized trials have shown a benefit to patent foramen ovale closure in reducing recurrence after cryptogenic stroke in the right patients.
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In-hospital vs. Telephone Availability of an Intensivist at Night
When overnight shifts were staffed by nighttime intensivists rather than residents with attending intensivists on call remotely, most nurses perceived improvements in clinical care, procedures, efficiency, communication, and job place comfort.
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Antibiotics and Adverse Events: Doctors, Do No Harm!
A retrospective study found that among 1,488 hospitalized patients who received an antibiotic, 298 (20%) experienced at least one antibiotic-associated adverse drug event.
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Optimizing Outcomes for Invasive Treatment of Long-standing, Persistent Atrial Fibrillation
In patients with long-standing, persistent atrial fibrillation, outcomes with an electrophysiologically guided thoracoscopic surgical ablation procedure were superior to a standard catheter approach.