Cardiology
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L-methylfolate for Bipolar Disorder
L-methylfolate improves some symptoms in major depression in people with type 1 bipolar disorder.
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Studies Find Cognitive Decline Reversible, Even if Patients Are ApoE4 Positive
Insulin resistance is associated with cognitive decline and Alzheimer’s disease. Patients who are positive for the apolipoprotein E4 gene are at increased risk for Alzheimer’s disease. This risk may be reversed by treating insulin resistance.
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Chinese Herbal Medicine in Chronic Hepatitis B Infection
Use of Chinese herbal medicine was associated with a significantly lower risk of developing hepatocellular carcinoma in patients receiving antiviral medication for chronic hepatitis B infection.
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Integrative Medicine for Chronic Pain: Acupuncture and Massage
There may be a role for acupuncture and massage in treating chronic pain.
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L-methylfolate for Bipolar Disorder
L-methylfolate improves some symptoms in major depression in people with type 1 bipolar.
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Rehabilitation From Neurological Insults: The Role of Music-based Interventions
The authors of this comprehensive review article found evidence for the use of music-based interventions as part of rehabilitation across a broad range of neurological disorders.
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Physician Burnout: A Multi-specialty Perspective
Although different specialties address the problem of physician burnout, studies suggest the most effect is gained from organizational interventions.
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Deflating Recruitment Maneuvers
Compared to the ARDSNet lower positive end-expiratory pressure (PEEP)/low tidal volume strategy, use of an “open lung ventilation” strategy consisting of aggressive alveolar recruitment maneuvers and higher PEEP is associated with higher mortality in patients with moderate to severe acute respiratory distress syndrome.
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ORBITA: Learning the Right Lessons From a Sham-controlled Trial of Angioplasty
In this sham-controlled trial of 200 patients with single-vessel coronary artery disease and stable angina, percutaneous coronary intervention did not increase exercise time significantly compared to a placebo procedure.
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Risk of Major Bleeding With Concurrent Medications in Atrial Fibrillation Patients Taking New Oral Anticoagulants
A large nationwide comprehensive clinical database showed that concomitant use of the new oral anticoagulants with amiodarone, fluconazole, rifampin, and phenytoin increases the risk of major bleeding.