Cardiology
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Zoster Vaccine Recombinant Adjuvanted (Shingrix)
Shingrix is indicated for the prevention of herpes zoster in adults ≥ 50 years of age.
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Fecal Microbiota Testing
Researchers have determined that persons with diabetes or inflammatory bowel disease — or people who have received recent antibacterial therapy — may exhibit very different microbiota profiles. Unfortunately, no one really knows what these differences mean in terms of your overall health.
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Is a Dabigatran Reversal Agent Effective?
A pragmatic clinical study of idarucizumab for counteracting the effects of the oral anticoagulant dabigatran showed rapid and complete reversal of its effects in patients with major bleeding or urgent surgery, without any adverse safety concerns.
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Can Medical Therapy Improve Functional Mitral Regurgitation?
Among patients who presented with heart failure with reduced ejection fraction and severe functional mitral regurgitation, mitral regurgitation improved in 38% of patients with medical management. Improvement in mitral regurgitation was associated with increased survival.
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Topical Cannabis for Wound Pain: A Case Series
For three people with continued pain despite conventional treatment for pyoderma gangrenosum, topical cannabis led to statistically significant pain relief for two of them.
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Low Serum 25-hydroxyvitamin D and Risk of Frequent Headache
Low vitamin D levels are associated with a range of neurovascular diseases, but little data are available on the association between vitamin D levels and headaches. This retrospective, cross-sectional study showed that low serum vitamin D levels were associated with a higher risk of frequent headaches in middle-aged/elderly Finnish men.
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Black seed (Nigella sativa) for Asthma: Minimal Effects
SYNOPSIS: Black seed, crushed, in capsule form, administered to 76 people with asthma in a single-blind, randomized study, showed some minimal improvements in some, but not all, components of spirometry and one serum cytokine after 12 weeks.
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Use of Essential Oils as an Alternative Treatment for Depression
The antidepressant effects of essential oils are promising, but more studies in humans beyond preliminary stages are needed.
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Tai Chi and Fall Risk
Tai chi practice in the older and at-risk population reduces the risk of falls (with the most robust results in the short-term) and may reduce the risk of injury from falls; no effect is seen when measuring time to the first fall.
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Do Antibiotics Reduce Hormonal Contraceptive Effectiveness?
This is a systematic review of studies evaluating the effect of concomitant non-rifamycin antibiotics use on hormonal contraceptive effectiveness. Although data are limited, there is no evidence to support the existence of drug interactions.