Cardiology
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When Can Surgeons Perform Aortic Valve Replacement Safely After a Stroke?
Interrogation of Danish administrative registry data demonstrated that a stroke within three to four months of aortic valve surgery was associated with a higher rate of perioperative stroke.
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Tailored Anticoagulation for Paroxysmal Atrial Fibrillation
Intermittent anticoagulation guided by continuous assessment of arrhythmia status in patients with low-to-moderate risk did not result in any strokes or thromboembolic events over a relatively short follow-up period. Such a strategy may be an alternative to chronic anticoagulation but requires further study.
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Invasive Procedures and the Risk of Infective Endocarditis
This large study suggests that several invasive, nondental medical procedures may be triggers for subsequent infective endocarditis, reopening the debate regarding prevention and management.
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Choosing a Vasopressor in Cardiogenic Shock: Is There a Difference?
When studying cardiogenic shock after acute myocardial infarction, these investigators found using epinephrine compared to norepinephrine produced similar effects on blood pressure and cardiac index, but resulted in a higher incidence of refractory cardiogenic shock.
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Are In-hospital Deaths Related to Community-acquired Pneumonia Preventable?
This secondary analysis of data from five tertiary care centers found that among patients hospitalized for community-acquired pneumonia, very few deaths potentially were related to a lapse in in-hospital quality of pneumonia care.
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Neighborhood Socioeconomic Status Associated With Infection Risk, But Not Sepsis
Based on a large, national, prospective cohort study, lower neighborhood socioeconomic status was associated with a higher incidence of hospitalizations for infection (but not sepsis) at presentation.
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Post-intensive Care Syndrome: What Happens After the ICU?
The number of ICU patients admitted annually continues to grow, with most recent estimates reaching 5.7 million. As there are growing numbers of critically ill patients, sepsis survivorship also has grown as a substantial public health concern, with a significant number of survivors diagnosed with post-intensive care syndrome (PICS). It is important to go beyond saving lives in the ICU and devote additional time and attention to preventing and treating the psychiatric, cognitive, and physical sequalae of ICU illness in the follow-up setting.
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Avatrombopag Tablets (Doptelet)
Doptelet is prescribed for adults with thrombocytopenia and chronic liver disease who are scheduled to undergo a medical procedure.
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‘The World Is Covered by a Thin Layer of Feces’
This study mirrors earlier work in New York City, which found that sand boxes and dog play areas often are contaminated with C. difficile.
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Oral Antibiotics May Increase the Risk for Nephrolithiasis
A case-control study found that receipt of an oral antibiotic in the preceding three to 12 months was associated with nephrolithiasis. The risk persisted up to five years, and younger patients were at increased risk.