Cardiology
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Sepsis-related Neurologic Dysfunction Strongly Associated With Long-term Mortality
In this multicenter, retrospective study, acute neurologic dysfunction was the organ dysfunction most strongly associated with short- and long-term mortality in patients surviving a sepsis hospitalization.
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Worse Than Snake Oil
Rattlesnake “pills” are basically dehydrated, ground up rattlesnake meat stuffed into gel caps. These may be sold locally in health food stores and are available online. The FDA has not reviewed nor approved this item.
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Invasive Procedures and the Risk of Infective Endocarditis
This large study suggests that several invasive, nondental medical procedures may be triggers for subsequent infective endocarditis, reopening the debate regarding prevention and management.
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Does Triple Inhaled Therapy for COPD Decrease Exacerbations Compared to Dual Therapy?
A single dose of inhaled triple therapy improved exacerbations compared to dual therapy in COPD patients.
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Cannabidiol for Pediatric Seizures
Three months of cannabidiol-enriched cannabis extract decreased mean monthly seizure frequency in children and young adults with refractory epilepsy.
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Vitamin D and Glycemic Control in Patients with Type 2 Diabetes
Findings from a meta-analysis show vitamin D supplementation was associated with improved glycemic control in vitamin D-deficient or non-obese patients with type 2 diabetes.
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Is There a Link Between Stopping Exercise and Depressive Symptoms?
SYNOPSIS: The authors of this review article found a suggestive link between stopping exercise and the onset of depressive symptoms in healthy adults, especially in women.
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Probiotic Use in Day Care Children
A 12-week intervention of daily supplementation with probiotics Bifidobacterium animalis subsp. lactis (BB-12) and Lactobacillus rhamnosus (LGG) 10 billion colony-forming units produced no reduction in the number of days absent from day care in Danish infants 8 to 14 months old.
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A Contemporary Review of Hypertension
Hypertension is a common and serious condition that contributes to an estimated 40% of deaths from coronary heart disease and stroke, and is the second leading cause of end-stage renal disease. Because of the importance and frequency of hypertension in primary care practices, we are devoting two issues to the subject. This issue focuses on the definition of blood pressure and current guidelines, risk factors, relationship to cardiovascular disease, blood pressure measurement, patient evaluation, and secondary causes. The next issue will cover treatments (pharmacological and non-pharmacological), initial therapy, relationship to various disease conditions (diabetes, ischemic heart disease, heart failure, chronic kidney disease, cerebrovascular disease, ischemic stroke, stroke prevention, atrial fibrillation, valvular heart disease, aortic regurgitation, sexual dysfunction), resistant hypertension, hypertensive crises and emergencies, preoperative management, and adherence strategies.
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Anticoagulation Management After Intracerebral Hemorrhage in Mechanical Heart Valve Patients
An observational study of patients with mechanical heart valves on oral anticoagulants who had an intracranial hemorrhage demonstrates that it generally is safe to resume anticoagulants after 14 days. However, in high-risk-for-thromboembolism patients, such as those with atrial fibrillation, restarting anticoagulants six to 13 days postoperative may be considered.