Cardiology
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Negative Fluid Balance on Day 3 Associated With Improved Outcomes in Critical Illness
In critically ill patients, a negative fluid balance on day 3 either spontaneously or with deresuscitative measures may be associated with lower mortality.
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ECMO vs. Optimal Protective Ventilation and Ancillary Therapies in Severe ARDS
Treatment of very severe acute respiratory distress syndrome with venovenous extracorporeal membrane oxygenation vs. lung-protective ventilation with aggressive ancillary therapy use demonstrated only a trend toward improved 60-day mortality.
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The Opioid Crisis in the ICU
A detailed exploration of the background of the opioid crisis and how it affects the ICU.
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Cannabidiol Oral Solution (Epidiolex)
Epidiolex is indicated for the treatment of seizures associated with Lennox-Gastaut syndrome or Dravet syndrome in patients ≥ 2 years of age.
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A Negative Nares Screen for MRSA Helps Exclude MRSA Pneumonia
The authors of a meta-analysis determined that nares screening for methicillin-resistant Staphylococcus aureus (MRSA) has a high specificity and negative predictive value for MRSA pneumonia.
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Vitamin D and Glycemic Control in Patients With Type 2 Diabetes
Findings from a meta-analysis show vitamin D supplementation was associated with improved glycemic control in vitamin D-deficient or non-obese patients with type 2 diabetes.
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Tailored Anticoagulation for Paroxysmal Atrial Fibrillation
Intermittent anticoagulation guided by continuous assessment of arrhythmia status in patients with low-to-moderate risk did not result in any strokes or thromboembolic events over a relatively short follow-up period.
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Timing of Protein Intake Does Not Influence Muscle Mass or Strength
The timing of protein intake during or between meals does not play a role in anabolic response, muscle strength, or functional outcomes.
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Runs of VT, or Aberrant Conduction?
A 47-year-old man presented with a history of intermittent dizziness over the previous two days. He was hemodynamically stable at the time the ECG in the figure was obtained. How would you interpret the rhythm? Is there any clue to a possible etiology for this patient’s arrhythmia?
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Plazomicin Injection (Zemdri)
Plazomicin is indicated for the treatment of adults ≥ 18 years of age with complicated urinary tract infections.