Cardiology
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Substance Abuse and Myocardial Infarction
Among patients ≤ 50 years of age with first myocardial infarctions, use of cocaine or marijuana increased the likelihood of an ST-segment elevation myocardial infarction and the subsequent risk of all-cause and cardiovascular mortality.
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Risk of Infective Endocarditis Revisited
In a comparison of patients with infective endocarditis (IE) and either bicuspid aortic valve (BAV) or mitral valve prolapse (MVP) vs. other IE patients at high or low to moderate risk of IE, BAV and MVP patients were more likely to exhibit viridans streptococci group infections of suspected odontogenic origin and cardiac complications at similar rates to high-risk patients.
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Home-based Detection of Undiagnosed Atrial Fibrillation
In patients with risk factors for atrial fibrillation, screening with a self-applied wearable ECG patch resulted in significantly increased rates of new atrial fibrillation diagnoses within four months, along with greater use of anticoagulants and healthcare resources.
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Canagliflozin Reduces Risk of Heart Failure Hospitalizations for Diabetic Patients
In type 2 diabetes mellitus patients with a higher risk of cardiovascular disease, canagliflozin lowered the risk of cardiovascular death or heart failure hospitalization. Patients with pre-existing heart failure may experience even greater benefit.
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Negative Fluid Balance on Day 3 Associated With Improved Outcomes in Critical Illness
In critically ill patients, a negative fluid balance on day 3 either spontaneously or with deresuscitative measures may be associated with lower mortality.
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ECMO vs. Optimal Protective Ventilation and Ancillary Therapies in Severe ARDS
Treatment of very severe acute respiratory distress syndrome with venovenous extracorporeal membrane oxygenation vs. lung-protective ventilation with aggressive ancillary therapy use demonstrated only a trend toward improved 60-day mortality.
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The Opioid Crisis in the ICU
A detailed exploration of the background of the opioid crisis and how it affects the ICU.
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Cannabidiol Oral Solution (Epidiolex)
Epidiolex is indicated for the treatment of seizures associated with Lennox-Gastaut syndrome or Dravet syndrome in patients ≥ 2 years of age.
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A Negative Nares Screen for MRSA Helps Exclude MRSA Pneumonia
The authors of a meta-analysis determined that nares screening for methicillin-resistant Staphylococcus aureus (MRSA) has a high specificity and negative predictive value for MRSA pneumonia.
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Vitamin D and Glycemic Control in Patients With Type 2 Diabetes
Findings from a meta-analysis show vitamin D supplementation was associated with improved glycemic control in vitamin D-deficient or non-obese patients with type 2 diabetes.