Cardiology
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Does a Gluten-free Diet Lower the Risk of Coronary Artery Disease in Adults?
A prospective, cohort study of health professionals conducted over 24 years revealed no significant association between long-term consumption of gluten and the risk of coronary artery disease in both adult men and women with no history of coronary artery disease.
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MRI for Patients With Pacemakers and Defibrillators
Performing an MRI on patients with pacemakers and defibrillators that were not MRI-conditional was not associated with any clinically significant changes in device parameters.
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Clinical Context and Outcomes in Stress Cardiomyopathy
An analysis of the International Takotsubo Registry showed that long-term mortality is similar to that observed in patients with acute coronary syndromes but varies widely depending on the triggering event.
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Tafamidis Improves Survival in Transthyretin Cardiac Amyloidosis
Treatment with tafamidis in transthyretin amyloid cardiomyopathy patients produced reductions in all-cause mortality and cardiovascular hospitalizations. This was the first medical therapy to demonstrate improved survival for patients with this condition.
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MitraClip Falls Short in First Randomized Trial Specific to Functional Mitral Regurgitation
The authors of a recent study concluded that percutaneous mitral valve repair with MitraClip did not significantly alter rates of death and heart failure hospitalization at one year over medical therapy alone.
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Who Really Needs Intensive Blood Pressure Control?
A patient baseline characteristics level analysis of the SPRINT and ACCORD trials resulted in the creation of a simple algorithm for identifying high-risk patients who experienced fewer major cardiac events without increased serious adverse events from intensive blood pressure therapy.
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Elagolix (Orilissa)
Elagolix is indicated for the management of moderate to severe pain associated with endometriosis.
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Treatment of Chronic Subdural Hematoma With Atorvastatin
The results of a recent study suggest that atorvastatin may be a safe and effective nonsurgical alternative for patients with chronic subdural hematoma.
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Inappropriate Outpatient Antibiotic Prescribing: The Need to Target Urgent Care Centers
Urgent care centers, which are part of a growth industry, are responsible for a large proportion of antibiotic prescriptions, including inappropriate prescriptions for acute respiratory diagnoses.
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Latent Tuberculosis Treatment With 4 Months of Rifampin Compared to 9 Months of Isoniazid
In an open-label trial, adults with latent tuberculosis infection were randomized to either four months of treatment with rifampin or nine months of treatment with isoniazid. The four-month rifampin regimen was non-inferior to nine months of isoniazid for prevention of active tuberculosis.