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This single-center prospective observational study reveals that the presence of 3 factors (low cough peak flow, high secretion volume, and poor neurologic score per a simple 4-task test) may be useful in predicting extubation failure.
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In surgical and trauma patients, a single oral application of 2 mL chlorhexidine gluconate was successful in reducing oral bacterial growth over a 72-hour period following intubation.
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A large multicenter prospective randomized double-blind trial found no difference in 28-day outcomes for fluid resuscitation with normal saline vs 4% albumin for a heterogeneous ICU population.
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Peripheral arterial disease may be stratified in severity by the ankle-brachial index, measured by dividing the ankle systolic BP by the brachial systolic BP.
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An NIH Consensus Panel has announced new recommendations for the diagnosis of celiac disease using new serologic testing.
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The newer, more potent, statin drugs are capable of reducing LDL cholesterol safely and tolerably in most patients thus making a target LDL of 50-70 mg/dL a practical goal, but how low is too low?
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Inhaled corticosteroids are the most effective pharmacologic agents in reducing exacerbations in asthmatics.
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The FDA has approved duloxetine for the treatment of depression and the management of the pain associated with diabetic peripheral neuropathy.
